Cellular and molecular immune response to chikungunya virus infection

ISB Tanabe, ELL Tanabe, EC Santos… - Frontiers in cellular …, 2018 - frontiersin.org
Chikungunya virus (CHIKV) is a re-emergent arthropod-borne virus (arbovirus) that causes a
disease characterized primarily by fever, rash and severe persistent polyarthralgia. In the …

Chikungunya virus: priority pathogen or passing trend?

G Montalvo Zurbia-Flores, A Reyes-Sandoval, YC Kim - Vaccines, 2023 - mdpi.com
Chikungunya virus (CHIKV) is considered a priority pathogen and a major threat to global
health. While CHIKV infections may be asymptomatic, symptomatic patients can develop …

The interplay of viral and host factors in chikungunya virus infection: targets for antiviral strategies

KZ Wong, JJH Chu - Viruses, 2018 - mdpi.com
Chikungunya virus (CHIKV) has re-emerged as one of the many medically important
arboviruses that have spread rampantly across the world in the past decade. Infected …

Mitochondrial protein BNIP3 regulates Chikungunya virus replication in the early stages of infection

L Echavarria-Consuegra, N Dinesh Kumar… - PLoS Neglected …, 2023 - journals.plos.org
Chikungunya virus (CHIKV) is a human pathogen causing outbreaks of febrile illness for
which vaccines and specific treatments remain unavailable. Autophagy-related (ATG) …

Role of autophagy during the replication and pathogenesis of common mosquito-borne flavi-and alphaviruses

L Echavarria-Consuegra, JM Smit… - Open …, 2019 - royalsocietypublishing.org
Arboviruses that are transmitted to humans by mosquitoes represent one of the most
important causes of febrile illness worldwide. In recent decades, we have witnessed a …

[HTML][HTML] Imidazonaphthyridine effects on Chikungunya virus replication: Antiviral activity by dependent and independent of interferon type 1 pathways

UEA Ruiz, IA Santos, VR Grosche, RS Fernandes… - Virus Research, 2023 - Elsevier
The Chikungunya virus (CHIKV) causes Chikungunya fever, a disease characterized by
symptoms such as arthralgia/polyarthralgia. Currently, there are no antivirals approved …

Peptide-Based Flavivirus Biosensors: From Cell Structure to Virological and Serological Detection Methods

A Muslihati, NLW Septiani, G Gumilar… - ACS Biomaterials …, 2024 - ACS Publications
In tropical and developing countries, mosquito-borne diseases by flaviviruses pose a
serious threat to public health. Early detection is critical for preventing their spread, but …

Transcriptome analysis of human macrophages upon chikungunya virus (CHIKV) infection reveals regulation of distinct signaling and metabolic pathways during the …

P Srivastava, S Chaudhary, S Malhotra, B Varma… - Heliyon, 2023 - cell.com
Macrophages are efficient reservoirs for viruses that enable the viruses to survive over a
longer period of infection. Alphaviruses such as chikungunya virus (CHIKV) are known to …

Nanomechanical and Vibrational Signature of Chikungunya Viral Particles

R Cardoso-Lima, JFSD Filho, ML de Araujo Dorneles… - Viruses, 2022 - mdpi.com
Chikungunya virus (CHIKV) belongs to the genus Alphaviridae, with a single-stranded
positive-sense RNA genome of 11.8 kbp encoding a polyprotein that generates both non …

Small molecule inhibitors targeting chikungunya virus

N Haese, J Powers, DN Streblow - Chikungunya Virus, 2020 - Springer
Chikungunya virus (CHIKV) infection in humans is rarely fatal but is often associated with
chronic joint and muscle pain. Chronic CHIKV disease is highly debilitating and is …