A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes

AM Dirir, M Daou, AF Yousef, LF Yousef - Phytochemistry Reviews, 2022 - Springer
Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate.
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …

Pharmaceutical drugs and natural therapeutic products for the treatment of type 2 diabetes mellitus

J Blahova, M Martiniakova, M Babikova, V Kovacova… - Pharmaceuticals, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is the most widespread form of diabetes, characterized by
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …

[HTML][HTML] Flavonoids against the SARS-CoV-2 induced inflammatory storm

A Liskova, M Samec, L Koklesova, SM Samuel… - Biomedicine & …, 2021 - Elsevier
The disease severity of COVID-19, especially in the elderly and patients with co-morbidities,
is characterized by hypercytokinemia, an exaggerated immune response associated with an …

Gallic acid: A versatile antioxidant with promising therapeutic and industrial applications

B Badhani, N Sharma, R Kakkar - Rsc Advances, 2015 - pubs.rsc.org
Oxidative stress, a result of an overproduction and accumulation of free radicals, is the
leading cause of several degenerative diseases such as cancer, atherosclerosis …

Flavonoids and gastrointestinal health: single molecule for multiple roles

H Lan, H Wang, C Chen, W Hu, C Ai… - Critical Reviews in …, 2024 - Taylor & Francis
Diet can be considered as one of the pivotal factors in regulating gastrointestinal health, and
polyphenols widely distributed in human daily diet. The polyphenols and their metabolites …

Flavonoids and the gastrointestinal tract: Local and systemic effects

PI Oteiza, CG Fraga, DA Mills, DH Taft - Molecular aspects of medicine, 2018 - Elsevier
The gastrointestinal (GI) tract plays a central role in the absorption, distribution, metabolism,
and excretion of flavonoids, which ultimately define the health effects of these bioactives …

Anthocyanin actions at the gastrointestinal tract: Relevance to their health benefits

PI Oteiza, E Cremonini, CG Fraga - Molecular Aspects of Medicine, 2023 - Elsevier
Anthocyanins (AC) are flavonoids abundant in the human diet, which consumption has been
associated to several health benefits, including the mitigation of cardiovascular disease …

The antidiabetic mechanisms of polyphenols related to increased glucagon-like peptide-1 (GLP1) and insulin signaling

JA Dominguez Avila, J Rodrigo Garcia… - Molecules, 2017 - mdpi.com
Type-2 diabetes mellitus (T2DM) is an endocrine disease related to impaired/absent insulin
signaling. Dietary habits can either promote or mitigate the onset and severity of T2DM …

Potential health benefits of phenolic compounds in grape processing by-products

JN Averilla, J Oh, HJ Kim, JS Kim, JS Kim - Food science and …, 2019 - Springer
Prevention emerges as a powerful approach in minimizing the risk of deleterious lifestyle
diseases because therapies do not necessarily guarantee a permanent cure. Accordingly …

Biodegradable polymeric nanoparticles loaded with flavonoids: A promising therapy for inflammatory bowel disease

M Li, Y Liu, B Weigmann - International Journal of Molecular Sciences, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a group of disorders that cause chronic non-specific
inflammation in the gastrointestinal (GI) tract, primarily affecting the ileum and colon. The …