Aims Both left ventricular (LV) diastolic dysfunction (LVDD) and hypertrophy (LVH) as
assessed by echocardiography are independent prognostic markers of future cardiovascular …

Background Clinical and echocardiographic features may carry diverse information about
the development of heart failure (HF). Therefore, we determined heterogeneity in clinical …

Aims Resting echocardiography is a valuable method for detecting subclinical heart failure
(HF) in patients with diabetes mellitus (DM). However, few studies have assessed the …

Background The intermediate metabolites associated with the development of
atherosclerotic cardiovascular disease (ASCVD) remain largely unknown. Thus, we …

Aims Biomarkers may provide insights into molecular mechanisms underlying heart
remodelling and dysfunction. Using a targeted proteomic approach, we aimed to identify …

Introduction The oxidative balance score (OBS) is a holistic measure that represents the
overall equilibrium between prooxidants and antioxidants in one's diet and lifestyle. Little …

Background and aims Circulating proteins reflecting subclinical vascular disease may
improve prediction of atherosclerotic cardiovascular disease (ASCVD). We applied feature …

Purpose As a powerful indicator of arterial stiffening, the brachial-ankle pulse wave velocity
(baPWV) has been extensively validated for predicting cardiovascular events. However …

Background Population studies investigating the contribution of immunometabolic
disturbances to heart dysfunction remain scarce. We combined high-throughput biomarker …

Peripheral blood pressure (PBP) is usually higher than central blood pressure (CBP) due to
pulse amplification; however, it is not well understood why cuff-measured PBP can be lower …