Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer

VR Yadav, S Prasad, B Sung, R Kannappan… - Toxins, 2010 - mdpi.com
Traditional medicine and diet has served mankind through the ages for prevention and
treatment of most chronic diseases. Mounting evidence suggests that chronic inflammation …

beta-Amyrin and alpha-amyrin acetate isolated from the stem bark of Alstonia boonei display profound anti-inflammatory activity

NN Okoye, DL Ajaghaku, HN Okeke… - Pharmaceutical …, 2014 - Taylor & Francis
Abstract Context: Alstonia boonei De Wild (Apocyanaceae) is used in ethnomedicine for the
management of malaria, ulcer, rhematic pain, toothache, and inflammatory disorders …

Rosmarinus officinalis L. hexane extract: phytochemical analysis, nanoencapsulation, and in silico, in vitro, and in vivo anti-photoaging potential evaluation

N Ibrahim, H Abbas, NS El-Sayed, HA Gad - Scientific Reports, 2022 - nature.com
A shift towards natural anti-aging ingredients has spurred the research to valorize
traditionally used plants. In this context, Rosmarinus officinalis L. was evaluated for its …

Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat

T Akihisa, N Kojima, T Kikuchi, K Yasukawa… - Journal of oleo …, 2010 - jstage.jst.go.jp
Four triterpene acetates, α-amyrin acetate (1a), β-amyrin acetate (2a), lupeol acetate (3a),
and butyrospermol acetate (4a), and four triterpene cinnamates, α-amyrin cinnamate (1c), β …

Ethnopharmacological Significance of Eclipta alba (L.) Hassk. (Asteraceae)

R Jahan, A Al-Nahain, S Majumder… - International scholarly …, 2014 - Wiley Online Library
Eclipta alba can be found growing wild in fallow lands of Bangladesh where it is considered
as a weed by farmers. Traditional medicinal systems of the Indian subcontinent countries as …

Antiinflammatory effect of phytosterols in experimental murine colitis model: prevention, induction, remission study

R Aldini, M Micucci, M Cevenini, R Fato, C Bergamini… - PloS one, 2014 - journals.plos.org
Phytosterols, besides hypocholesterolemic effect, present anti-inflammatory properties. Little
information is available about their efficacy in Inflammatory Bowel Disease (IBD). Therefore …

Beyond cholesterol-lowering effects of plant sterols: clinical and experimental evidence of anti-inflammatory properties

RA Othman, MH Moghadasian - Nutrition reviews, 2011 - academic.oup.com
Inflammation is a strong risk factor for cardiovascular disease. Dietary plant sterols are
known to reduce plasma cholesterol levels and thereby reduce cardiovascular risk. Recent …

Brazilian medicinal plants described by 19th century European naturalists and in the Official Pharmacopoeia

MGL Brandão, NNS Zanetti, P Oliveira… - Journal of …, 2008 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: The American flora represents one of the
world's wealthiest sources of material with pharmacological activity due to its biodiversity …

Activation of cannabinoid receptors by the pentacyclic triterpene α, β-amyrin inhibits inflammatory and neuropathic persistent pain in mice

KABS da Silva, AF Paszcuk, GF Passos, ES Silva… - PAIN®, 2011 - Elsevier
In this study, we report that α, β-amyrin, a plant-derived pentacyclic triterpene, reduced
persistent inflammatory and neuropathic hyperalgesia in mice by a direct activation of the …