Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

BACKGROUND Female cancer patients are offered 'banking'of gametes before starting
fertility-threatening cancer therapy. Transplants of fresh and frozen ovarian tissue between …

BACKGROUND Young female adult and adolescent cancer patients facing life-preserving
but fertility-threatening chemo-or radiation-therapy are increasingly seeking options to …

Intracellular Ca 2+ stores play a central role in the regulation of cellular [Ca 2+] i and the
generation of complex [Ca 2+] signals such as oscillations and waves. Ca 2+ signalling is of …

In the mammalian ovary a small number of follicles are steadily recruited from the quiescent
pool to undergo development. Follicle loss, maintenance and growth are strictly controlled …

Anti-cancer therapy, particularly chemotherapy, damages ovarian follicles and promotes
ovarian failure. The only pharmacological means for protecting the ovaries from …

BACKGROUND Ovarian tissue cryopreservation is a promising technique to safeguard
fertility in cancer patients. However, in some types of cancer, there is a risk of transmitting …

BACKGROUND In vitro follicle growth is a promising fertility preservation strategy in which
ovarian follicles are cultured to produce mature and fertilization-competent oocytes …

In vitro ovarian follicle cultures may provide fertility-preserving options to women facing
premature infertility due to cancer therapies. An encapsulated three-dimensional (3-D) …

This study aimed to assess the effects of platelet-rich plasma (PRP) on growth and survival
of isolated early human follicles in a three-dimensional culture system. After fresh and …