Computer aided drug design: success and limitations
Over the last few decades, computer-aided drug design has emerged as a powerful
technique playing a crucial role in the development of new drug molecules. Structure-based …
technique playing a crucial role in the development of new drug molecules. Structure-based …
Modulation of neurotrophic signaling pathways by polyphenols
Polyphenols are an important class of phytochemicals, and several lines of evidence have
demonstrated their beneficial effects in the context of a number of pathologies including …
demonstrated their beneficial effects in the context of a number of pathologies including …
Flavonoids and their metabolites: prevention in cardiovascular diseases and diabetes
The occurrence of atherosclerosis and diabetes is expanding rapidly worldwide. These two
metabolic disorders often co-occur, and are part of what is often referred to as the metabolic …
metabolic disorders often co-occur, and are part of what is often referred to as the metabolic …
Coffee and lower risk of type 2 diabetes: arguments for a causal relationship
H Kolb, S Martin, K Kempf - Nutrients, 2021 - mdpi.com
Prospective epidemiological studies concur in an association between habitual coffee
consumption and a lower risk of type 2 diabetes. Several aspects of these studies support a …
consumption and a lower risk of type 2 diabetes. Several aspects of these studies support a …
Viral hepatitis, cholesterol metabolism, and cholesterol-lowering natural compounds
JW Liou, H Mani, JH Yen - International Journal of Molecular Sciences, 2022 - mdpi.com
Hepatitis is defined as inflammation of the liver; it can be acute or chronic. In chronic cases,
the prolonged inflammation gradually damages the liver, resulting in liver fibrosis, cirrhosis …
the prolonged inflammation gradually damages the liver, resulting in liver fibrosis, cirrhosis …
Polyherbal mixture ameliorates hyperglycemia, hyperlipidemia and histopathological changes of pancreas, kidney and liver in a rat model of type 1 diabetes
Ethnopharmacological relevance One of the commonly prescribed 'anti-diabetic'polyherbal
mixtures by European herbalists is made of Rubus fruticosus and Vaccinium myrtillus …
mixtures by European herbalists is made of Rubus fruticosus and Vaccinium myrtillus …
[HTML][HTML] Potential dual inhibitors of PCSK-9 and HMG-R from natural sources in cardiovascular risk management
Atherosclerotic cardiovascular disease (ASCVD) stands amongst the leading causes of
mortality worldwide and has attracted the attention of world's leading pharmaceutical …
mortality worldwide and has attracted the attention of world's leading pharmaceutical …
In Vitro and In Silico Studies of the Molecular Interactions of Epigallocatechin-3-O-gallate (EGCG) with Proteins That Explain the Health Benefits of Green Tea
Green tea has been shown to have beneficial effects on many diseases such as cancer,
obesity, inflammatory diseases, and neurodegenerative disorders. The major green tea …
obesity, inflammatory diseases, and neurodegenerative disorders. The major green tea …
Ultrasound assisted extraction of phenolic compounds from a jujube by-product with valuable bioactivities
F Berkani, ML Serralheiro, F Dahmoune, A Ressaissi… - Processes, 2020 - mdpi.com
Jujube plant is a potential source of polyphenols with biological propreties. The purpose of
this study was to investigate the application of ultrasound technique for extracting phenolic …
this study was to investigate the application of ultrasound technique for extracting phenolic …
Antidiabetic effects of polyherbal mixture made of Centaurium erythraea, Cichorium intybus and Potentilla erecta
A Petrović, V Madić, G Stojanović, I Zlatanović… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance The polyherbal mixture made of Centaurium erythraea
aerial parts and Cichorium intybus roots and Potentilla erecta rhizomes has been used for …
aerial parts and Cichorium intybus roots and Potentilla erecta rhizomes has been used for …