Proton pump inhibitors (PPI) and histamine-2 receptor antagonists (H2RA) are commonly
used medications in neonates and infants for the treatment of gastroesophageal reflux …

Background Reducing preterm birth and stillbirth and improving outcomes for babies born
too soon is essential to reduce under-5 mortality globally. In the context of a rapidly evolving …

Necrotizing enterocolitis (NEC) is a critical gastrointestinal emergency with substantial
morbidity and mortality risks, especially for very low-birth-weight (VLBW) infants, and unclear …

Approximately two-thirds of US infants receive infant formula (IF) as a primary or sole
nutritional source during the first six months of life. IF is available in a variety of commercial …

Gastroesophageal reflux (GER) is the retrograde movement of gastric (and sometimes
duodenal) contents into the esophagus. While the majority of GER is physiologic, for …

Background The use of histamine-2 receptor antagonists (H2RA) in neonates is still debated
because of possible risk of infection, necrotizing enterocolitis (NEC) and increased mortality …

Objectives Preterm children are exposed to many medications in neonatal intensive care
units, but little is known about the effect of prematurity on medication use throughout infancy …

Objective: To evaluate the use of off-label and unlicensed medications in preterm infants
hospitalized in a neonatal intensive care unit. Methods: This nonconcurrent cohort study …

Objectives This mixed-methods feasibility study aimed to explore parents' and medical
practitioners' views on the acceptability and design of a clinical trial to determine whether …

Objective To determine the extent of off-label and unlicensed prescribing in hospitalized
newborns and to identify patient-related risk factors associated with off-label prescribing …