Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

Oxidative stress and inflammation have been recognized as important contributors to the risk
of chronic non-communicable diseases. Polyunsaturated fatty acids (PUFAs) may regulate …

Several lines of preclinical and clinical research have confirmed that chronic low-grade
inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …

The consumption of Western-type calorically rich diets combined with chronic overnutrition
and a sedentary lifestyle in Western societies evokes a state of chronic metabolic …

Cardiovascular diseases (CVD) are complex entities with heterogenous pathophysiologic
mechanisms and increased oxidative stress has been viewed as one of the potential …

Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …

Alterations on the immune system caused by omega-3 fatty acids have been described for
30 years. This family of polyunsaturated fatty acids exerts major alterations on the activation …

Omega‐3 polyunsaturated fatty acids (omega‐3 PUFAs), which are essential fatty acids that
humans should obtain from diet, have potential benefits for human health. In addition to …

Obesity is the most common cause of insulin resistance, and the current obesity epidemic is
driving a parallel rise in the incidence of T2DM. It is now widely recognized that chronic …

Patients with well-controlled LDL (low-density lipoprotein) levels still have residual
cardiovascular risk associated with elevated triglycerides. Epidemiological studies have …