The endosomal recycling pathway—at the crossroads of the cell

MJ O'sullivan, AJ Lindsay - International journal of molecular sciences, 2020 - mdpi.com
The endosomal recycling pathway lies at the heart of the membrane trafficking machinery in
the cell. It plays a central role in determining the composition of the plasma membrane and …

Modification of phosphoinositides by the Shigella effector IpgD during host cell infection

G Tran Van Nhieu, P Latour-Lambert… - Frontiers in cellular and …, 2022 - frontiersin.org
Shigella, the causative agent of bacillary dysentery, subvert cytoskeletal and trafficking
processes to invade and replicate in epithelial cells using an arsenal of bacterial effectors …

Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection

S Mehto, KK Jena, R Yadav, S Priyadarsini… - The EMBO …, 2022 - embopress.org
Abstract The NOD1/2‐RIPK2 is a key cytosolic signaling complex that activates NF‐κB pro‐
inflammatory response against invading pathogens. However, uncontrolled NF‐κB signaling …

The recycling endosome and bacterial pathogens

SC Allgood, MR Neunuebel - Cellular microbiology, 2018 - Wiley Online Library
Bacterial pathogens have developed a wide range of strategies to survive within human
cells. A number of pathogens multiply in a vacuolar compartment, whereas others can …

[HTML][HTML] Post-translational targeting of Rab35 by the effector IcsB of Shigella determines intracellular bacterial niche formation

N Mellouk, A Lensen, N Lopez-Montero, M Gil… - Cell Reports, 2024 - cell.com
Escape from the bacterial-containing vacuole (BCV) is a key step of Shigella host cell
invasion. Rab GTPases subverted to in situ-formed macropinosomes in the vicinity of the …

Sitting in the driver's seat: Manipulation of mammalian cell Rab GTPase functions by apicomplexan parasites

I Coppens, JD Romano - Biology of the Cell, 2020 - Wiley Online Library
Many intracellular microbial pathogens subvert, disrupt or otherwise modulate host
membrane trafficking pathways to establish a successful infection. Among them, bacteria …

[HTML][HTML] Shigella generates distinct IAM subpopulations during epithelial cell invasion to promote efficient intracellular niche formation

L Sanchez, A Lensen, MG Connor, M Hamon… - European Journal of …, 2024 - Elsevier
The facultative intracellular pathogen Shigella flexneri invades non-phagocytic epithelial gut
cells. Through a syringe-like apparatus called type 3 secretion system, it injects effector …

[PDF][PDF] Investigating the interaction of Legionella pneumophila with host endocytic recycling pathways

SC Allgood - 2022 - udspace.udel.edu
Legionella pneumophila is an opportunistic intracellular pathogen which can be found to
infected human alveolar macrophages to cause a severe form of pneumonia known as …

Guarding the Vacuole: How Legionella T4SS Substrate SdhA Maintains Vacuole Integrity

IS Anand - 2019 - search.proquest.com
Legionella pneumophila is a Gram-negative, intracellular pathogen that targets amoebal
species in aquatic environments and alveolar macrophages in humans. To sustain …

[引用][C] SHIGELLA FLEXNERI REQUIRES THE HOST SCAFFOLD PROTEIN RACK1 TO MODULATE ACTIN POLYMERIZATION, PROMOTING INFECTION

K Valenzuela - 2022