Depression is a mental illness frequently accompanied by disordered energy metabolism. A
dysregulated hypothalamus pituitary adrenal axis response with aberrant glucocorticoids …

In mammals, the functional development of the cochlea requires the tight regulation of
multiple molecules and signalling pathways including fibroblast growth factors, bone …

Amyotrophic lateral sclerosis (ALS) is a genetically and phenotypically heterogeneous
disease results in the loss of motor neurons. Mounting information points to involvement of …

Steroid hormone signaling pathways are critical for organismal development and act
through binding to nuclear receptors (NRs) driving transcriptional regulation. In this review …

BACKGROUND: Perivascular adipose tissue (PVAT) is vital for vascular homeostasis, and
PVAT dysfunction is associated with increased atherosclerotic plaque burden. But the …

Haploinsufficient mutation in arginine and glutamine-rich protein 1 (Arglu1), a newly
identified pre-mRNA splicing regulator, may be linked to neural developmental disorders …

Arginine and glutamate rich 1 (ARGLU1) is a poorly understood cellular protein with
functions in RNA splicing and transcription. Computational prediction suggests that ARGLU1 …

Cyclin-dependent kinases (CDKs) are key players in cell cycle regulation and transcription.
The CDK-family member Cdk10 is important for neural development and can act as a …

Stable intronic sequence RNAs (sisRNAs) are stable, long noncoding RNAs containing
intronic sequences. While sisRNAs have been found across diverse species, their level of …

Hypertrophic scar (HS) is a severe skin disorder characterized by excessive extracellular
matrix production and abnormal function of fibroblasts. Recent studies have demonstrated …