Opportunities and challenges in long-read sequencing data analysis

SL Amarasinghe, S Su, X Dong, L Zappia, ME Ritchie… - Genome biology, 2020 - Springer
Long-read technologies are overcoming early limitations in accuracy and throughput,
broadening their application domains in genomics. Dedicated analysis tools that take into …

Host–transposon interactions: conflict, cooperation, and cooption

RL Cosby, NC Chang, C Feschotte - Genes & development, 2019 - genesdev.cshlp.org
Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …

Mosquito vector competence for dengue is modulated by insect-specific viruses

RP Olmo, YMH Todjro, ERGR Aguiar… - Nature …, 2023 - nature.com
Aedes aegypti and A. albopictus mosquitoes are the main vectors for dengue virus (DENV)
and other arboviruses, including Zika virus (ZIKV). Understanding the factors that affect …

[HTML][HTML] Non-canonical odor coding in the mosquito

M Herre, OV Goldman, TC Lu, G Caballero-Vidal, Y Qi… - Cell, 2022 - cell.com
Aedes aegypti mosquitoes are a persistent human foe, transmitting arboviruses including
dengue when they feed on human blood. Mosquitoes are intensely attracted to body odor …

3D genomics across the tree of life reveals condensin II as a determinant of architecture type

C Hoencamp, O Dudchenko, AMO Elbatsh… - Science, 2021 - science.org
We investigated genome folding across the eukaryotic tree of life. We find two types of three-
dimensional (3D) genome architectures at the chromosome scale. Each type appears and …

Large-scale comparative analyses of tick genomes elucidate their genetic diversity and vector capacities

N Jia, J Wang, W Shi, L Du, Y Sun, W Zhan, JF Jiang… - Cell, 2020 - cell.com
Among arthropod vectors, ticks transmit the most diverse human and animal pathogens,
leading to an increasing number of new challenges worldwide. Here we sequenced and …

A high-quality Ixodes scapularis genome advances tick science

S De, SB Kingan, C Kitsou, DM Portik, SD Foor… - Nature Genetics, 2023 - nature.com
Ixodes spp. and related ticks transmit prevalent infections, although knowledge of their
biology and development of anti-tick measures have been hindered by the lack of a high …

[HTML][HTML] Climate and urbanization drive mosquito preference for humans

NH Rose, M Sylla, A Badolo, J Lutomiah, D Ayala… - Current Biology, 2020 - cell.com
The majority of mosquito-borne illness is spread by a few mosquito species that have
evolved to specialize in biting humans, yet the precise causes of this behavioral shift are …

The enormous repetitive Antarctic krill genome reveals environmental adaptations and population insights

C Shao, S Sun, K Liu, J Wang, S Li, Q Liu, BE Deagle… - Cell, 2023 - cell.com
Antarctic krill (Euphausia superba) is Earth's most abundant wild animal, and its enormous
biomass is vital to the Southern Ocean ecosystem. Here, we report a 48.01-Gb chromosome …

Development of a confinable gene drive system in the human disease vector Aedes aegypti

M Li, T Yang, NP Kandul, M Bui, S Gamez, R Raban… - Elife, 2020 - elifesciences.org
Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …