In eukaryotic cells, the budding and fusion of intracellular transport vesicles is carefully
orchestrated in space and time. Locally, a vesicle's source compartment, its cargo, and its …

The endolysosomal system specializes in degrading cellular components and is crucial to
maintaining homeostasis and adapting rapidly to metabolic and environmental cues. Cells …

Three epibiotic Epistylis species, ie, Epistylis weishanensis sp. nov., Epistylis daphniae
Fauré-Fremiet, 1905, and Epistylis pygmaeum (Ehrenberg, 1838) Foissner et al., 1999, were …

The organelle paralogy hypothesis (OPH) aims to explain the evolution of non-
endosymbiotically derived organelles. It predicts that lineage-specific pathways or …

In ciliates, membrane cisternae called alveoli interpose between the plasma membrane and
the cytoplasm, posing a barrier to endocytic and exocytic membrane trafficking. One …

Abstract The Organelle Paralogy Hypothesis (OPH) posits a mechanism to explain the
evolution of non-endosymbiotically derived organelles, predicting that lineage-specific …

Although an established model organism, Tetrahymena thermophila remains comparatively
inaccessible to high throughput screens, and alternative bioinformatic approaches still rely …

Regulated vesicle exocytosis, as in the case of highly specialised synaptic vesicle secretion,
is controlled by a set of evolutionarily conserved proteins. Many of these proteins predate …

I studied the evolution and cell biology of Paramecium tetraurelia—a model ciliate with over
40,000 distinct protein-coding genes resulting from as many as three ancient whole-genome …