The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Cardiovascular disease (CVD) remains a worldwide public health concern despite decades
of research and the availability of numerous targeted therapies. While the intrinsic …

Coronary artery disease (CAD) is a major cardiovascular disease responsible for high
morbidity and mortality worldwide. The major pathophysiological basis of CAD is …

SARS-CoV-2 infection or COVID-19 has become a worldwide pandemic; however, effective
treatment for COVID-19 remains to be established. Along with acute respiratory distress …

Oxytocin (OT) emerges as a drug for the treatment of diabetes and obesity. The entire OT
system is synthesized in the rat and human heart. The direct myocardial infusion with OT into …

The oxytocin receptor (OXTR) is a G protein-coupled receptor with a diverse repertoire of
intracellular signaling pathways, which are activated in response to binding oxytocin (OXT) …

The neuropeptide hormone oxytocin, which is released from the posterior pituitary gland, is
involved in a number of physiological processes. Understanding of its effects is gradually …

Angiotensin-converting enzyme (ACE) and ACE2 play a critical role in the renin–angiotensin
system (RAS) by altering angiotensin II (ANGII) levels, thus governing its deleterious effects …

Oxytocin (OXT) has been shown to suppress appetite, induce weight loss, and improve
glycemic control and lipid metabolism in several species, including humans, monkeys, and …

Cardiovascular disease (CVD) remains the leading cause of death worldwide, despite
multiple treatment options. In addition to elevated lipid levels, oxidative stress and …