The development and progression of diabetic kidney disease (DKD), a highly prevalent
complication of diabetes mellitus, are influenced by both genetic and environmental factors …

The kidney is arguably the most important target of microvascular damage in diabetes. A
substantial proportion of individuals with diabetes will develop kidney disease owing to their …

Diabetic kidney disease (DKD) is a devastating microvascular complication associated with
diabetes mellitus. Recently, the major focus of glomerular lesions of DKD has partly shifted …

Abstract Type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease
(CKD), are recognized among the most disruptive public health issues of the current century …

There is very limited human renal sodium gradient-dependent glucose transporter protein
(SGLT2) mRNA and protein expression data reported in the literature. The first aim of this …

Although pathologic classifications exist for several renal diseases, including IgA
nephropathy, focal segmental glomerulosclerosis, and lupus nephritis, a uniform …

Diabetic nephropathy is one of the leading causes of end‐stage renal disease and creates
heavy healthcare burdens globally. Dysfunction of mesangial cells and podocytes …

Diabetic nephropathy is a common kidney condition in patients with diabetes mellitus, which
can result in renal failure. Pyroptosis, the process of pro-inflammatory programmed cell …

Diabetic nephropathy (DN), a severe microvascular complication frequently associated with
both type 1 and type 2 diabetes mellitus, is a leading cause of renal failure. The condition …

Insights from epidemiological, clinical and basic research are illuminating the interplay
between metabolic disorders, cardiovascular disease (CVD) and kidney dysfunction, termed …