[HTML][HTML] 2, 3-Dihydroquinazolin-4 (1 H)-one as a privileged scaffold in drug design

M Badolato, F Aiello, N Neamati - RSC advances, 2018 - pubs.rsc.org
2, 3-Dihydroquinazolin-4-one (DHQ) belongs to the class of nitrogen-containing heterocyclic
compounds representing a core structural component in various biologically active …

Ultrasonic energy for construction of bioactive heterocycles

O Kamble, R Chatterjee, R Dandela, S Shinde - Tetrahedron, 2022 - Elsevier
The ultrasonic energy has been revisited and applied for the synthesis of bioactive
molecules in a short time and green method. These compounds can exhibit anticancer …

Solvent-free, mechanochemically scalable synthesis of 2, 3-dihydroquinazolin-4 (1H)-one using Brønsted acid catalyst

G Yashwantrao, VP Jejurkar, R Kshatriya… - ACS Sustainable …, 2019 - ACS Publications
Although the synthesis of novel N-heterocyclic molecules is extremely demanding as well as
challenging, the involvement of toxic solvents often triggers environmental safety concerns …

Fe3O4@SiO2@TiO2-OSO3H: an efficient hierarchical nanocatalyst for the organic quinazolines syntheses

A Maleki, T Kari, M Aghaei - Journal of Porous Materials, 2017 - Springer
A sulfonic acid functionalized titanium dioxide quasi-superparamagnetic nanocatalyst Fe 3
O 4@ SiO 2@ TiO 2-OSO 3 H with average size of 61 nm and semispherical shape with …

CuO nanoparticles catalyzed simple and efficient synthesis of 2, 3-dihydroquinazolin-4 (1H)-ones and quinazolin-4 (3H)-ones under ultrasound irradiation in aqueous …

J Zhang, D Ren, Y Ma, W Wang, H Wu - Tetrahedron, 2014 - Elsevier
A CuO nanoparticle-catalyzed one-pot process has engineered for the preparation of
diverse quinazolinones from the readily available isatoic anhydride, aldehydes and amine …

Microwave‐assisted synthesis as an efficient method to enhance the catalytic activity of Zr‐based metal organic framework UiO‐66 in a heterocyclization reaction

LHT Nguyen, TTT Nguyen, YT Dang… - Asian Journal of …, 2019 - Wiley Online Library
Zr‐based metal‐organic frameworks have been considered promising heterogeneous
catalysts in various reactions. It has been proven that the defect sites in these frameworks …

[HTML][HTML] An efficient approach for the green synthesis of biologically active 2, 3-dihydroquinazolin-4 (1 H)-ones using a magnetic EDTA coated copper based …

S Kohli, G Rathee, S Hooda, R Chandra - RSC advances, 2023 - pubs.rsc.org
2, 3-Dihydroquinazolinone derivatives are known for antiviral, antimicrobial, analgesic, anti-
inflammatory, and anticancer activities. However, recent approaches used for their synthesis …

Hydroxyapatite nanoparticles (HAP NPs): a green and efficient heterogeneous catalyst for three-component one-pot synthesis of 2, 3-dihydroquinazolin-4 (1 H)-one …

N Razavi, B Akhlaghinia - New Journal of Chemistry, 2016 - pubs.rsc.org
Hydroxyapatite nanoparticles (HAP NPs) are found to be an efficient catalyst for synthesis of
2, 3-dihydroquinazolin-4 (1H)-one derivatives in aqueous media via a three-component one …

Wang resin catalysed sonochemical synthesis of pyrazolo [4, 3-d] pyrimidinones and 2, 3-dihydroquinazolin-4 (1H)-ones: Identification of chorismate mutase inhibitors …

S Shukla, RN Rao, H Bhuktar, RK Edwin, T Jamma… - Bioorganic …, 2023 - Elsevier
The enzyme chorismate mutase (or CM that is vital for the survival of bacteria) is an
interesting pharmacological target for the identification of new anti-tubercular agents. The 5 …

[HTML][HTML] A Discovery-Based Metabolomic Approach Using UPLC-Q-TOF-MS/MS Reveals Potential Antimalarial Compounds Present in Artemisia annua L.

H Shi, Z Wang, F Xu, J Li, J Li, M Wang - International Journal of …, 2022 - mdpi.com
In 1972, Nobel laureate Youyou Tu's research team conducted clinical trials on the dried
material of Artemisia annua L. from Beijing extracted by ether and then treated with alkali …