Vitamin B12  – Physiology, Production and Application

J Marie Sych, C Lacroix… - Industrial biotechnology of …, 2016 - Wiley Online Library
Cobalamin or B12 is an important group of water‐soluble compounds belonging to the
cobalt corrinoid family. This chapter provides an overview of B12 chemistry and physical …

Modularity of nitrogen‐oxide reducing soil bacteria: linking phenotype to genotype

CA Roco, LL Bergaust, LR Bakken… - Environmental …, 2017 - Wiley Online Library
Model denitrifiers convert to N2, but it appears that a significant fraction of natural
populations are truncated, conducting only one or two steps of the pathway. To better …

Fermentative production of vitamin B12 by Propionibacterium shermanii and Pseudomonas denitrificans and its promising health benefits: A review

A Tripathi, VK Pandey, PS Panesar… - Food Science & …, 2024 - Wiley Online Library
Cobalamin, generally known as vitamin B12, is a crucial component required for humans in
several physiological processes. It has been produced from sources that are derived from …

Use of acetate for the production of 3-hydroxypropionic acid by metabolically-engineered Pseudomonas denitrificans

S Zhou, S Lama, J Jiang, M Sankaranarayanan… - Bioresource …, 2020 - Elsevier
The use of acetate as carbon feedstock can enhance sustainability and economics of the
current bio-productions. This study explored the potential of acetate for the production of 3 …

Coenzyme B12 synthesis as a baseline to study metabolite contribution of animal microbiota

A Danchin, S Braham - Microbial biotechnology, 2017 - Wiley Online Library
Microbial communities thrive in a number of environments. Exploration of their microbiomes–
their global genome–may reveal metabolic features that contribute to the development and …

Development of Pseudomonas asiatica as a host for the production of 3-hydroxypropionic acid from glycerol

TT Nguyen, S Lama, SK Ainala… - Bioresource …, 2021 - Elsevier
Pseudomonas asiatica C1, which could grow on glucose and aerobically synthesize
coenzyme B 12, was isolated and developed as a microbial cell factory for the production of …

Coenzyme B12 can be produced by engineered Escherichia coli under both anaerobic and aerobic conditions

Y Ko, S Ashok, SK Ainala… - Biotechnology …, 2014 - Wiley Online Library
Abstract Coenzyme B12 (Vitamin B12) is one of the most complex biomolecules and an
essential cofactor required for the catalytic activity of many enzymes. Pseudomonas …

Development of a deletion mutant of Pseudomonas denitrificans that does not degrade 3-hydroxypropionic acid

S Zhou, S Ashok, Y Ko, DM Kim, S Park - Applied microbiology and …, 2014 - Springer
Pseudomonas denitrificans is a gram-negative bacterium that can produce vitamin B 12
under aerobic conditions. Recently, recombinant strains of P. denitrificans overexpressing a …

Inducible gene expression system by 3-hydroxypropionic acid

S Zhou, SK Ainala, E Seol, TT Nguyen, S Park - Biotechnology for Biofuels, 2015 - Springer
Abstract Background 3-Hydroxypropionic acid (3-HP) is an important platform chemical that
boasts a variety of industrial applications. Gene expression systems inducible by 3-HP, if …

Differential Deep RNA Sequencing for Diagnostic Detection of Microbial Infections in Inflammatory Cardiomyopathy

W Huang, C Yin, PA Lento, PV Adem… - Circulation: Genomic …, 2024 - ahajournals.org
BACKGROUND: Inflammatory heart disease can be triggered by a variety of causes, both
infectious and noninfectious in nature. We hypothesized that inflammatory cardiomyopathy …