Importance of the pig as a human biomedical model
JK Lunney, A Van Goor, KE Walker… - Science translational …, 2021 - science.org
Pigs have substantial potential as biomedical models for studying human developmental
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …
Intermuscular adipose tissue in metabolic disease
Intermuscular adipose tissue (IMAT) is a distinct adipose depot described in early reports as
a 'fatty replacement'or 'muscle fat infiltration'that was linked to ageing and neuromuscular …
a 'fatty replacement'or 'muscle fat infiltration'that was linked to ageing and neuromuscular …
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody …
There is need for effective and affordable vaccines against SARS-CoV-2 to tackle the
ongoing pandemic. In this study, we describe a protein nanoparticle vaccine against SARS …
ongoing pandemic. In this study, we describe a protein nanoparticle vaccine against SARS …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …
immunology and flow cytometry community. They provide the theory and key practical …
[HTML][HTML] SARS-CoV-2 infection, clinical features and outcome of COVID-19 in United Kingdom nursing homes
NSN Graham, C Junghans, R Downes, C Sendall… - Journal of Infection, 2020 - Elsevier
Summary Objectives To understand SARS-Co-V-2 infection and transmission in UK nursing
homes in order to develop preventive strategies for protecting the frail elderly residents …
homes in order to develop preventive strategies for protecting the frail elderly residents …
Pig genome functional annotation enhances the biological interpretation of complex traits and human disease
The functional annotation of livestock genomes is crucial for understanding the molecular
mechanisms that underpin complex traits of economic importance, adaptive evolution and …
mechanisms that underpin complex traits of economic importance, adaptive evolution and …
Understanding respiratory microbiome–immune system interactions in health and disease
SK Di Simone, I Rudloff, CA Nold-Petry… - Science translational …, 2023 - science.org
Interactions between the developing microbiome and maturing immune system in early life
are critical for establishment of a homeostasis beneficial to both host and commensals. The …
are critical for establishment of a homeostasis beneficial to both host and commensals. The …
Natural and experimental SARS-CoV-2 infection in domestic and wild animals
DA Meekins, NN Gaudreault, JA Richt - Viruses, 2021 - mdpi.com
SARS-CoV-2 is the etiological agent responsible for the ongoing COVID-19 pandemic,
which continues to spread with devastating effects on global health and socioeconomics …
which continues to spread with devastating effects on global health and socioeconomics …
[HTML][HTML] The immunology of the porcine skin and its value as a model for human skin
A Summerfield, F Meurens, ME Ricklin - Molecular immunology, 2015 - Elsevier
The porcine skin has striking similarities to the human skin in terms of general structure,
thickness, hair follicle content, pigmentation, collagen and lipid composition. This has been …
thickness, hair follicle content, pigmentation, collagen and lipid composition. This has been …
Application areas of 3D bioprinting
IT Ozbolat, W Peng, V Ozbolat - Drug discovery today, 2016 - Elsevier
Highlights•Bioprinting is a powerful technology in tissue and organ fabrication.•Bioprinting
has gained significant interest in medicine and pharmaceutics.•Bioprinting has been widely …
has gained significant interest in medicine and pharmaceutics.•Bioprinting has been widely …