Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

The gastrointestinal tract communicates with the nervous system through a bidirectional
network of signaling pathways called the gut-brain axis, which consists of multiple …

Animals must adapt their dietary choices to meet their nutritional needs. How these needs
are detected and translated into nutrient-specific appetites that drive food-choice behaviours …

The animal foregut is the first tissue to encounter ingested food, bacteria, and viruses. We
characterized the adult Drosophila foregut using transcriptomics to better understand how it …

A complex cascade of events leads to the initiation and maintenance of a behavioral act in
response to both internally and externally derived stimuli. These events are part of a …

Endocrine signaling networks control diverse biological processes and life history traits
across metazoans. In both invertebrate and vertebrate taxa, steroid hormones regulate …

Dietary restriction (DR) slows aging in many animals, while in some cases, the sensory
signals from diet alone are sufficient to retard or accelerate lifespan. The digestive tract is a …

Neurons contribute to the regeneration of projected tissues; however, it remains unclear
whether they are involved in the non-innervated tissue regeneration. Herein, we showed …

Introduction: Insulin-like peptides (Ilps) play crucial roles in nearly all life stages of insects.
Ilp8 is involved in developmental stability, stress resistance and female fecundity in several …

This review briefly summarizes 50 years of research on insect neuropeptide and peptide
hormone (collectively abbreviated NPH) signaling, starting with the sequencing of proctolin …