Numerous investigations have shown that mitochondrial dysfunction is a major mechanism
of drug-induced liver injury, which involves the parent drug or a reactive metabolite …

Background: Obesity is often associated with nonalcoholic fatty liver disease (NAFLD),
which refers to a large spectrum of hepatic lesions including fatty liver, nonalcoholic …

Obesity is commonly associated with nonalcoholic fatty liver (NAFL), a benign condition
characterized by hepatic lipid accumulation. However, NAFL can progress in some patients …

Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease in developed
countries. Its frequency is increasing in the general population mostly due to the widespread …

The Fontan procedure has undergone many modifications since first being performed on a
patient with tricuspid valve atresia in 1968. It is now the procedure of choice for individuals …

Several drugs have been associated with the potential for drug-induced hepatic steatosis
(DIHS) and/or phospholipidosis (DIPL), a lysosomal storage disorder. Drug-induced hepatic …

Amiodarone has been associated with adverse events that may restrict its use. We
performed a meta-analysis of placebo-controlled trials to assess the relative risk of adverse …

Drug‐induced liver injury (DILI) encompasses a spectrum of liver diseases from acute and
chronic hepatitis, cholestatic syndromes, and vascular lesions through to benign and …

Abstract Purpose of the Review This review serves to update the reader on emerging data
regarding a spectrum of drug-induced liver injury (DILI) outcomes that lie between complete …

Obesity is one of the most common chronic conditions in the world. Its management is
difficult, partly due to the multiple associated comorbidities including fatty liver, diabetes …