Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles
The application of nanomedicines is increasing rapidly with the promise of targeted and
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …
Current and novel polymeric biomaterials for neural tissue engineering
R Boni, A Ali, A Shavandi, AN Clarkson - Journal of biomedical science, 2018 - Springer
The nervous system is a crucial component of the body and damages to this system, either
by of injury or disease, can result in serious or potentially lethal consequences. Restoring …
by of injury or disease, can result in serious or potentially lethal consequences. Restoring …
PLGA-based nanoparticles: an overview of biomedical applications
Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …
biodegradable polymers. Among the different polymers developed to formulate polymeric …
GDNF, NGF and BDNF as therapeutic options for neurodegeneration
SJ Allen, JJ Watson, DK Shoemark, NU Barua… - Pharmacology & …, 2013 - Elsevier
Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor
(NGF) and brain-derived neurotrophic factor (BDNF) are important for the survival …
(NGF) and brain-derived neurotrophic factor (BDNF) are important for the survival …
Advances in Parkinson's disease: 200 years later
When James Parkinson described the classical symptoms of the disease he could hardly
foresee the evolution of our understanding over the next two hundred years. Nowadays …
foresee the evolution of our understanding over the next two hundred years. Nowadays …
Biomaterials for promoting brain protection, repair and regeneration
Biomaterials are likely to have an increasingly important role in the treatment of nervous
system disorders. Recently developed biomaterials can enable and augment the targeted …
system disorders. Recently developed biomaterials can enable and augment the targeted …
Nanomedicine and drug delivery systems in cancer and regenerative medicine
E Garbayo, S Pascual‐Gil… - Wiley …, 2020 - Wiley Online Library
Nanomedicine and drug delivery technologies play a prominent role in modern medicine,
facilitating better treatments than conventional drugs. Nanomedicine is being increasingly …
facilitating better treatments than conventional drugs. Nanomedicine is being increasingly …
Stem cell technology for neurodegenerative diseases
JS Lunn, SA Sakowski, J Hur… - Annals of neurology, 2011 - Wiley Online Library
Over the past 20 years, stem cell technologies have become an increasingly attractive
option to investigate and treat neurodegenerative diseases. In the current review, we …
option to investigate and treat neurodegenerative diseases. In the current review, we …
Novel focused ultrasound gene therapy approach noninvasively restores dopaminergic neuron function in a rat Parkinson's disease model
Therapies capable of decelerating, or perhaps even halting, neurodegeneration in
Parkinson's disease (PD) remain elusive. Clinical trials of PD gene therapy testing the …
Parkinson's disease (PD) remain elusive. Clinical trials of PD gene therapy testing the …
Non-invasive, neuron-specific gene therapy by focused ultrasound-induced blood-brain barrier opening in Parkinson's disease mouse model
CY Lin, HY Hsieh, CM Chen, SR Wu, CH Tsai… - Journal of Controlled …, 2016 - Elsevier
Focused ultrasound (FUS)-induced with microbubbles (MBs) is a promising technique for
noninvasive opening of the blood-brain barrier (BBB) to allow targeted delivery of …
noninvasive opening of the blood-brain barrier (BBB) to allow targeted delivery of …