Integrin inactivators: balancing cellular functions in vitro and in vivo
D Bouvard, J Pouwels, N De Franceschi… - Nature reviews Molecular …, 2013 - nature.com
Integrins mediate cell–matrix and cell–cell interactions and integrate extracellular cues to
the cytoskeleton and cellular signalling pathways. Integrin function on the cell surface is …
the cytoskeleton and cellular signalling pathways. Integrin function on the cell surface is …
The dual role of filamin A in cancer: can't live with (too much of) it, can't live without it
RM Savoy, PM Ghosh - Endocrine-related cancer, 2013 - erc.bioscientifica.com
Filamin A (FlnA) has been associated with actin as cytoskeleton regulator. Recently its role
in the cell has come under scrutiny for FlnA's involvement in cancer development. FlnA was …
in the cell has come under scrutiny for FlnA's involvement in cancer development. FlnA was …
The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation
Neuroblastoma is an embryonal tumor of the sympathetic nervous system and the most
common extracranial tumor of childhood. By sequencing transcriptomes of low-and high-risk …
common extracranial tumor of childhood. By sequencing transcriptomes of low-and high-risk …
Dissecting the expression landscape of RNA-binding proteins in human cancers
B Kechavarzi, SC Janga - Genome biology, 2014 - Springer
Background RNA-binding proteins (RBPs) play important roles in cellular homeostasis by
controlling gene expression at the post-transcriptional level. Results We explore the …
controlling gene expression at the post-transcriptional level. Results We explore the …
The function and pathogenic mechanism of filamin A
J Zhou, X Kang, H An, Y Lv, X Liu - Gene, 2021 - Elsevier
Filamin A (FLNa) is an actin-binding protein, which participates in the formation of the
cytoskeleton, anchors a variety of proteins in the cytoskeleton and regulates cell adhesion …
cytoskeleton, anchors a variety of proteins in the cytoskeleton and regulates cell adhesion …
Upregulated cytoskeletal proteins promote pathological angiogenesis in moyamoya disease
S He, J Zhang, Z Liu, Y Wang, X Hao, X Wang, Z Zhou… - Stroke, 2023 - Am Heart Assoc
BACKGROUND: Moyamoya disease (MMD) is a rare progressive vascular disease that
leads to intracranial internal carotid artery stenosis and eventual occlusion. However, its …
leads to intracranial internal carotid artery stenosis and eventual occlusion. However, its …
Filamin A regulates cardiovascular remodeling
S Bandaru, C Ala, AX Zhou, LM Akyürek - International journal of …, 2021 - mdpi.com
Filamin A (FLNA) is a large actin-binding cytoskeletal protein that is important for cell motility
by stabilizing actin networks and integrating them with cell membranes. Interestingly, a C …
by stabilizing actin networks and integrating them with cell membranes. Interestingly, a C …
Complex roles of filamin-A mediated cytoskeleton network in cancer progression
J Yue, S Huhn, Z Shen - Cell & bioscience, 2013 - Springer
Abstract Filamin-A (FLNA), also called actin-binding protein 280 (ABP-280), was originally
identified as a non-muscle actin binding protein, which organizes filamentous actin into …
identified as a non-muscle actin binding protein, which organizes filamentous actin into …
Exploration of oxygen-induced retinopathy model to discover new therapeutic drug targets in retinopathies
M Vähätupa, TAH Järvinen… - Frontiers in …, 2020 - frontiersin.org
Oxygen-induced retinopathy (OIR) is a pure hypoxia-driven angiogenesis model and the
most widely used model for ischemic retinopathies, such as retinopathy of prematurity …
most widely used model for ischemic retinopathies, such as retinopathy of prematurity …
Filamin A: insights into its exact role in cancers
QQ Shao, TP Zhang, WJ Zhao, ZW Liu, L You… - Pathology & Oncology …, 2016 - Springer
Filamin A (FlnA) is a well-known actin cross-linking protein. It serves as a scaffold for over 90
binding partners and involves in multiple cell functions, of which cell migration and adhesion …
binding partners and involves in multiple cell functions, of which cell migration and adhesion …