Computer-aided design techniques for flow-based microfluidic lab-on-a-chip systems

X Huang, TY Ho, W Guo, B Li, K Chakrabarty… - ACM Computing …, 2021 - dl.acm.org
As one of the most promising lab-on-a-chip systems, flow-based microfluidic biochips are
being increasingly used for automatically executing various laboratory procedures in biology …

Design automation for continuous-flow microfluidic biochips: A comprehensive review

G Liu, H Huang, Z Chen, H Lin, H Liu, X Huang, W Guo - Integration, 2022 - Elsevier
Continuous-flow microfluidic biochips (CFMBs), also known as lab-on-a-chip platforms, have
attracted considerable attentions in the past two decades and have been widely used in …

Columba 2.0: A co-layout synthesis tool for continuous-flow microfluidic biochips

TM Tseng, M Li, DN Freitas, T McAuley… - … on Computer-Aided …, 2017 - ieeexplore.ieee.org
Continuous-flow microfluidic large-scale integration (mLSI) shows increasing importance in
biological/chemical fields, thanks to its advantages in miniaturization and high throughput …

Close-to-optimal placement and routing for continuous-flow microfluidic biochips

A Grimmer, Q Wang, H Yao, TY Ho… - 2017 22nd Asia and …, 2017 - ieeexplore.ieee.org
Continuous-flow microfluidics rapidly evolved in the last decades as a solution to automate
laboratory procedures in molecular biology and biochemistry. Therefore, the physical design …

Random design of microfluidics

J Wang, P Brisk, WH Grover - Lab on a Chip, 2016 - pubs.rsc.org
In this work we created functional microfluidic chips without actually designing them. We
accomplished this by first generating a library of thousands of different random microfluidic …

Computer-aided design of microfluidic circuits

EE Tsur - Annual review of biomedical engineering, 2020 - annualreviews.org
Microfluidic devices developed over the past decade feature greater intricacy, increased
performance requirements, new materials, and innovative fabrication methods …

Columba: Co-layout synthesis for continuous-flow microfluidic biochips

TM Tseng, M Li, B Li, TY Ho… - Proceedings of the 53rd …, 2016 - dl.acm.org
Continuous-flow microfluidics have evolved rapidly in the last decades, due to their
advantages in effective and accurate control. However, complex control results in …

Transport or store? Synthesizing flow-based microfluidic biochips using distributed channel storage

C Liu, B Li, H Yao, P Pop, TY Ho… - Proceedings of the 54th …, 2017 - dl.acm.org
Flow-based microfluidic biochips have attracted much attention in the EDA community due
to their miniaturized size and execution efficiency. Previous research, however, still follows …

Physical co-design of flow and control layers for flow-based microfluidic biochips

Q Wang, H Zou, H Yao, TY Ho… - IEEE Transactions on …, 2017 - ieeexplore.ieee.org
Flow-based microfluidic biochips are attracting increasing attention with successful
applications in biochemical experiments, point-of-care diagnosis, etc. Existing works in …

Microfluidic design for concentration gradient generation using artificial neural network

W Ji, TY Ho, J Wang, H Yao - IEEE Transactions on Computer …, 2019 - ieeexplore.ieee.org
According to the complexity of human physiology and variability among individuals, eg,
genes, environment, lifestyle exposures, etc., personalized medicine aims to synthesize the …