Endometrial carcinoma: molecular alterations involved in tumor development and progression

A Yeramian, G Moreno-Bueno, X Dolcet, L Catasus… - Oncogene, 2013 - nature.com
In the western world, endometrial carcinoma (EC) is the most common cancer of the female
genital tract. The annual incidence has been estimated at 10–20 per 100 000 women. Two …

[HTML][HTML] The Role of ApoE expression and variability of its glycosylation in human reproductive health in the light of current information

M Kacperczyk, A Kmieciak, EM Kratz - International Journal of Molecular …, 2021 - mdpi.com
Apolipoprotein E (ApoE), a 34-kDa glycoprotein, as part of the high-density lipoprotein
(HDL), has antioxidant, anti-inflammatory and antiatherogenic properties. The variability of …

[HTML][HTML] Apolipoprotein E Overexpression Is Associated With Tumor Progression and Poor Survival in Colorectal Cancer

Z Zhao, S Zou, X Guan, M Wang, Z Jiang, Z Liu… - Frontiers in …, 2018 - frontiersin.org
Apolipoprotein E (ApoE) plays a key role in tumorigenesis and progression, such as cell
proliferation, angiogenesis and metastasis. ApoE overexpression was associated with …

[HTML][HTML] Glycosylation and its research progress in endometrial cancer

C Pu, Biyuan, K Xu, Y Zhao - Clinical and Translational Oncology, 2022 - Springer
Endometrial cancer (EC) is one of the most common tumors in the female reproductive
system, which seriously threatens women's health, particularly in developed countries. 13 …

Prognostic biomarkers in endometrial and ovarian carcinoma

X Matias-Guiu, B Davidson - Virchows Archiv, 2014 - Springer
This article reviews the main prognostic and predictive biomarkers of endometrial (EC) and
ovarian carcinoma (OC). In EC, prognosis still relies on conventional pathological features …

[HTML][HTML] A Label-free proteomic approach for the identification of biomarkers in the exosome of endometrial cancer serum

E Sommella, V Capaci, M Aloisio, E Salviati… - Cancers, 2022 - mdpi.com
Simple Summary Endometrial cancers (ECs) are mostly adenocarcinomas arising from the
inner part of the uterus. The identification of serum biomarkers may be useful for an early …

[HTML][HTML] Tumor Apolipoprotein E is a key checkpoint blocking anti-tumor immunity in mouse melanoma

X Wu, P Srinivasan, M Basu, P Zhang… - Frontiers in …, 2022 - frontiersin.org
Immunotherapy is a key modality in the treatment of cancer, but many tumors remain
immune resistant. The classic mouse model of B16-F10 melanoma is immune resistant even …

[HTML][HTML] Meta-analysis of gene expression studies in endometrial cancer identifies gene expression profiles associated with aggressive disease and patient outcome

TA O'Mara, M Zhao, AB Spurdle - Scientific reports, 2016 - nature.com
Although endometrioid endometrial cancer (EEC; comprising~ 80% of all endometrial
cancers diagnosed) is typically associated with favourable patient outcome, a significant …

[HTML][HTML] Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues

S Hashimoto, Y Tabuchi, H Yurino, Y Hirohashi… - Scientific reports, 2017 - nature.com
Single cell transcriptome analysis of a cancer tissue can provide objective assessment of
subtype population or the activation of each of various microenvironment component cells …

[HTML][HTML] Expression and clinical significance of complement C3, complement C4b1 and apolipoprotein E in pancreatic cancer

J Chen, W Wu, C Zhen, H Zhou, R Yang… - Oncology …, 2013 - spandidos-publications.com
Pancreatic cancer (PC) remains a devastating disease with a five‑year survival rate of< 5%.
The difficulty in making an early diagnosis and the frequent occurrence of metastasis are …