Lipoxygenases (LOXs) are dioxygenases that catalyze the formation of corresponding
hydroperoxides from polyunsaturated fatty acids such as linoleic acid and arachidonic acid …

Leprosy (Hansen's disease) is a human infectious disease whose etiological agent,
Mycobacterium leprae, was identified by GHA Hansen in the 19th century. Despite the high …

Eicosanoids are biologically active lipid mediators, comprising prostaglandins, leukotrienes,
thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to …

As complex common diseases, asthma and allergic diseases are caused by the interaction
of multiple genetic variants with a variety of environmental factors. Candidate-gene studies …

Asthma is a frequent disease, mainly characterized by airway inflammation, in which drug
therapy is crucial in its management. The potential of pharmacogenomics testing in asthma …

Asthma and allergic diseases are complex conditions caused by a combination of genetic
and environmental factors. More than 100 genes have been associated with asthma and …

Purpose We determined whether variants in genes associated with genital tubercle (the
anlage for the penis) and early urethral development were associated with hypospadias in …

The burden and disparity of asthma in race/ethnic minorities present a significant challenge.
In this review, we will evaluate data on asthma epidemiology in minorities, examine potential …

Arachidonate lipoxygenase (ALOX) enzymes metabolize arachidonic acid to generate
potent inflammatory mediators and play an important role in inflammation‐associated …

Asthma is a chronic disease that has a significant impact on quality of life and is particularly
important in children and adolescents, in part due to the higher incidence of allergies in …