A noradrenergic and serotonergic hypothesis of the linkage between epilepsy and affective disorders
PC Jobe, JW Dailey, JF Wernicke - Critical Reviews™ in …, 1999 - dl.begellhouse.com
Noradrenergic and/or serotonergic deficits, as well as other abnormalities, may contribute to
predisposition to some epilepsies and depressions. Evidence for this hypothesis stems from …
predisposition to some epilepsies and depressions. Evidence for this hypothesis stems from …
Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory
Emotional arousal enhances perception and memory of high-priority information but impairs
processing of other information. Here, we propose that, under arousal, local glutamate levels …
processing of other information. Here, we propose that, under arousal, local glutamate levels …
Mechanisms of action and clinical efficacy of NMDA receptor modulators in mood disorders
Although the biogenic amine models have provided meaningful links between clinical
phenomena and pharmacological management of mood disorders (MDs), the onset of …
phenomena and pharmacological management of mood disorders (MDs), the onset of …
Inhibition of neuronal Ca2+ influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices
K Fink, W Meder, DJ Dooley… - British journal of …, 2000 - Wiley Online Library
Cytosolic calcium ion concentrations ([Ca2+] i) were measured in rat neocortical
synaptosomes using fura‐2, and depolarization of synaptosomal membranes was induced …
synaptosomes using fura‐2, and depolarization of synaptosomal membranes was induced …
Release-enhancing glycine-dependent presynaptic NMDA receptors exist on noradrenergic terminals of hippocampus
A Pittaluga, M Raiteri - European journal of pharmacology, 1990 - Elsevier
The release of [3 H] noradrenaline ([3 H] NA) in superfused rat hippocampal synaptosomes
was increased concentration dependently by N-methyl-D-aspartate (NMDA). Glycine (1 μM) …
was increased concentration dependently by N-methyl-D-aspartate (NMDA). Glycine (1 μM) …
Integrated application of transcriptomics and metabolomics provides insights into the larval metamorphosis of pearl oyster (Pinctada fucata martensii)
J Zhang, X Xiong, Y Deng, Z Zheng, C Yang, X Du - Aquaculture, 2021 - Elsevier
Larval metamorphosis, the planktonic larvae transited into benthic juveniles, is a short
important phase for mollusks. However, information about the mechanism of its larval …
important phase for mollusks. However, information about the mechanism of its larval …
Presynaptic glutamate receptors regulate noradrenaline release from isolated nerve terminals
JKT Wang, H Andrews, V Thukral - Journal of neurochemistry, 1992 - Wiley Online Library
The wide‐ranging neuronal actions of excitatory amino acids, such as glutamate, are
thought to be mediated mainly by postsynaptic N‐methyl‐D‐aspartate (NMDA) and non …
thought to be mediated mainly by postsynaptic N‐methyl‐D‐aspartate (NMDA) and non …
NMDA receptor antagonists suppress behaviors but not norepinephrine turnover or locus coeruleus unit activity induced by opiate withdrawal
K Rasmussen, RW Fuller, ME Stockton… - European journal of …, 1991 - Elsevier
Pretreatment with the non-competitive NMDA (N-methyl-D-aspartate) antagonist MK801
(0.5, 1.0 mg/kg, sc) suppressed the behavioral signs of withdrawal in morphine-dependent …
(0.5, 1.0 mg/kg, sc) suppressed the behavioral signs of withdrawal in morphine-dependent …
Modulation of NMDA and dopaminergic neurotransmissions by sigma ligands: possible implications for the treatment of psychiatric disorders
G Debonnel, C de Montigny - Life Sciences, 1996 - Elsevier
Sigma (σ) receptors, improperly classified as belonging to the opiate receptor family when
discovered in 1976, were subsequently confused with phencyclidine binding sites for …
discovered in 1976, were subsequently confused with phencyclidine binding sites for …
Presynaptic release‐regulating NMDA receptors in isolated nerve terminals: A narrative review
A Pittaluga - British Journal of Pharmacology, 2021 - Wiley Online Library
The existence of presynaptic, release‐regulating NMDA receptors in the CNS has been long
matter of discussion. Most of the reviews dedicated to support this conclusion have …
matter of discussion. Most of the reviews dedicated to support this conclusion have …