A noradrenergic and serotonergic hypothesis of the linkage between epilepsy and affective disorders

PC Jobe, JW Dailey, JF Wernicke - Critical Reviews™ in …, 1999 - dl.begellhouse.com
Noradrenergic and/or serotonergic deficits, as well as other abnormalities, may contribute to
predisposition to some epilepsies and depressions. Evidence for this hypothesis stems from …

Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory

M Mather, D Clewett, M Sakaki… - Behavioral and Brain …, 2016 - cambridge.org
Emotional arousal enhances perception and memory of high-priority information but impairs
processing of other information. Here, we propose that, under arousal, local glutamate levels …

Mechanisms of action and clinical efficacy of NMDA receptor modulators in mood disorders

M Ghasemi, C Phillips, A Fahimi, MW McNerney… - Neuroscience & …, 2017 - Elsevier
Although the biogenic amine models have provided meaningful links between clinical
phenomena and pharmacological management of mood disorders (MDs), the onset of …

Inhibition of neuronal Ca2+ influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices

K Fink, W Meder, DJ Dooley… - British journal of …, 2000 - Wiley Online Library
Cytosolic calcium ion concentrations ([Ca2+] i) were measured in rat neocortical
synaptosomes using fura‐2, and depolarization of synaptosomal membranes was induced …

Release-enhancing glycine-dependent presynaptic NMDA receptors exist on noradrenergic terminals of hippocampus

A Pittaluga, M Raiteri - European journal of pharmacology, 1990 - Elsevier
The release of [3 H] noradrenaline ([3 H] NA) in superfused rat hippocampal synaptosomes
was increased concentration dependently by N-methyl-D-aspartate (NMDA). Glycine (1 μM) …

Integrated application of transcriptomics and metabolomics provides insights into the larval metamorphosis of pearl oyster (Pinctada fucata martensii)

J Zhang, X Xiong, Y Deng, Z Zheng, C Yang, X Du - Aquaculture, 2021 - Elsevier
Larval metamorphosis, the planktonic larvae transited into benthic juveniles, is a short
important phase for mollusks. However, information about the mechanism of its larval …

Presynaptic glutamate receptors regulate noradrenaline release from isolated nerve terminals

JKT Wang, H Andrews, V Thukral - Journal of neurochemistry, 1992 - Wiley Online Library
The wide‐ranging neuronal actions of excitatory amino acids, such as glutamate, are
thought to be mediated mainly by postsynaptic N‐methyl‐D‐aspartate (NMDA) and non …

NMDA receptor antagonists suppress behaviors but not norepinephrine turnover or locus coeruleus unit activity induced by opiate withdrawal

K Rasmussen, RW Fuller, ME Stockton… - European journal of …, 1991 - Elsevier
Pretreatment with the non-competitive NMDA (N-methyl-D-aspartate) antagonist MK801
(0.5, 1.0 mg/kg, sc) suppressed the behavioral signs of withdrawal in morphine-dependent …

Modulation of NMDA and dopaminergic neurotransmissions by sigma ligands: possible implications for the treatment of psychiatric disorders

G Debonnel, C de Montigny - Life Sciences, 1996 - Elsevier
Sigma (σ) receptors, improperly classified as belonging to the opiate receptor family when
discovered in 1976, were subsequently confused with phencyclidine binding sites for …

Presynaptic release‐regulating NMDA receptors in isolated nerve terminals: A narrative review

A Pittaluga - British Journal of Pharmacology, 2021 - Wiley Online Library
The existence of presynaptic, release‐regulating NMDA receptors in the CNS has been long
matter of discussion. Most of the reviews dedicated to support this conclusion have …