The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …

Estrogens and androgens influence the growth and maintenance of the mammalian
skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause …

Abstract Objective To update the “Testosterone Therapy in Men With Androgen Deficiency
Syndromes” guideline published in 2010. Participants The participants include an Endocrine …

Sarcopenia is defined as the age-related loss of muscle mass and strength or physical
performance. Increased amounts of adipose tissue often accompany sarcopenia, a condition …

Importance Cognitive decline is a common and feared aspect of aging. Mild cognitive
impairment (MCI) is defined as the symptomatic predementia stage on the continuum of …

Background Testosterone is the standard treatment for male hypogonadism, but there is
uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide …

Background: Age-associated declines in muscle mass and function are major risk factors for
an impaired ability to carry out activities of daily living, falls, prolonged recovery time after …

The term sarcopenia refers to the loss of muscle mass that occurs with ageing. On the basis
of study results showing that muscle mass is only moderately related to functional outcomes …

Testosterone is a key hormone in the pathology of metabolic diseases such as obesity. Low
testosterone levels are associated with increased fat mass (particularly central adiposity) …

Testosterone (T) is the principal male sex hormone. As men age, T levels typically fall.
Symptoms of low T include decreased libido, vasomotor instability, and decreased bone …