Dyneins make up a family of AAA+ motors that move toward the minus end of microtubules.
Cytoplasmic dynein is responsible for transporting intracellular cargos in interphase cells …

Axonemal dyneins form the inner and outer rows of arms associated with the doublet
microtubules of motile cilia. These enzymes convert the chemical energy released from …

In motile cilia, a mechanoregulatory network is responsible for converting the action of
thousands of dynein motors bound to doublet microtubules into a single propulsive …

Cilia and flagella are highly conserved organelles that have diverse roles in cell motility and
sensing extracellular signals. Motility defects in cilia and flagella often result in primary …

Cilia are hairlike protrusions that project from the surface of eukaryotic cells and play key
roles in cell signaling and motility. Ciliary motility is regulated by the conserved nexin-dynein …

Dyneins are large minus‐end‐directed microtubule motors. Each dynein contains at least
one dynein heavy chain (DHC) and a variable number of intermediate chains (IC), light …

Ciliary motility is crucial for the development and health of many organisms. Motility depends
on the coordinated activity of multiple dynein motors arranged in a precise pattern on the …

Understanding the molecular architecture of the flagellum is crucial to elucidate the bending
mechanism produced by this complex organelle. The current known structure of the …

The fallopian tube is lined with a highly complex folded epithelium surrounding a lumen that
progressively narrows. To study the influence of this labyrinthine complexity on sperm …

Dynein ATPases power diverse microtubule-based motilities. Each dynein motor domain
comprises a ring-like head containing six AAA+ modules and N-and C-terminal regions …