Cardiovascular diseases are the leading cause of global mortality. Over the past two
decades, researchers have tried to provide novel solutions for end-stage heart failure to …

A promising paradigm to regenerative medicine involves the application of biomaterials,
which makes a spurt of progress in the past 20 years. Of various biomaterials, decellularized …

Excessive cardiac fibrosis impairs cardiac repair after myocardial infarction (MI). In this work,
an injectable composite hydrogel integrating natural biomaterials, exosomes, and bioactive …

Myocardial infarction caused by coronary artery obstruction results in the loss of heart
muscle, which is subsequently replaced by scar tissue with limited therapeutic options …

Engineered human cardiac tissues have been utilized for various biomedical applications,
including drug testing, disease modeling, and regenerative medicine. However, the …

Cardiac patches made up of polymer scaffolds and heart muscle cells have received great
attention as a promising construct to repair damaged heart tissue and improve its function …

Ischemic cardiomyopathy (ICM) affect millions of patients globally. Decellularized
extracellular matrix materials (dECM) have components, microstructure and mechanical …

Tissue engineering combines principles of engineering and biology to generate living tissue
equivalents for drug testing, disease modeling, and regenerative medicine. As techniques …

Myocardial infarction (MI) is one of the common cardiovascular diseases that occurs with a
blockage in one or more of the coronary arteries to lead to the damage of the myocardium …

Myocardial infarction is one of the major causes of morbidity and mortality worldwide.
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …