Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Stimuli that promote cell migration, such as chemokines, cytokines, and growth factors in
metazoans and cyclic AMP in Dictyostelium, activate signaling pathways that control …

The light-based control of ion channels has been transformative for the neurosciences, but
the optogenetic toolkit does not stop there. An expanding number of proteins and cellular …

Multiple protein families, each with a distinct function, provide the traffic signals for
leukocytes. The selectin family of adhesion molecules (Figure 2) has an N-terminal domain …

Cancer cells possess a broad spectrum of migration and invasion mechanisms. These
include both individual and collective cell-migration strategies. Cancer therapeutics that are …

Actin stress fibers are one of the major cytoskeletal structures in fibroblasts and are linked to
the plasma membrane at focal adhesions. rho, a ras-related GTP-binding protein, rapidly …

We investigate the motion of a run-and-tumble particle (RTP) in one dimension. We find the
exact probability distribution of the particle with and without diffusion on the infinite line, as …

Invasive tumor dissemination in vitro and in vivo involves the proteolytic degradation of ECM
barriers. This process, however, is only incompletely attenuated by protease inhibitor–based …

Direct-current (DC) electric fields are present in all developing and regenerating animal
tissues, yet their existence and potential impact on tissue repair and development are …

The social amoebae are exceptional in their ability to alternate between unicellular and
multicellular forms. Here we describe the genome of the best-studied member of this group …