Medicinal plants in the treatment of depression: Evidence from preclinical studies

I Moragrega, JL Ríos - Planta medica, 2021 - thieme-connect.com
Medicinal plants and their extracts are natural remedies with enormous potential for treating
various diseases, including depression and anxiety. In the case of depression, hundreds of …

Structural Characterization and Immunomodulatory Activity of a Novel Polysaccharide from Lepidium meyenii

M Zhang, G Wang, F Lai, H Wu - Journal of agricultural and food …, 2016 - ACS Publications
A novel polysaccharide named as MC-1 was isolated from the roots of Lepidium meyenii
using a water extraction method. Structural characterization revealed that MC-1 had an …

Matrine ameliorates anxiety and depression-like behaviour by targeting hyperammonemia-induced neuroinflammation and oxidative stress in CCl4 model of liver …

A Khan, B Shal, M Naveed, FA Shah, A Atiq, NU Khan… - Neurotoxicology, 2019 - Elsevier
Acute or chronic liver injury is associated with hyperammonemia which induced
neuroinflammation and oxidative stress in the brain. Neuroinflammation, oxidative stress …

Erinacine A-Enriched Hericium erinaceus Mycelium Produces Antidepressant-Like Effects through Modulating BDNF/PI3K/Akt/GSK-3β Signaling in Mice

CH Chiu, CC Chyau, CC Chen, LY Lee… - International journal of …, 2018 - mdpi.com
Antidepressant-like effects of ethanolic extract of Hericium erinaceus (HE) mycelium
enriched in erinacine A on depressive mice challenged by repeated restraint stress (RS) …

Characterization of effective phytochemicals in traditional Chinese medicine by mass spectrometry

CY Chen, YH Li, Z Li, MR Lee - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Abstract Traditional Chinese medicines (TCMs) have been widely used in clinical and
healthcare applications around the world. The characterization of the phytochemical …

Preservation of Cognitive Function by Lepidium meyenii (Maca) Is Associated with Improvement of Mitochondrial Activity and Upregulation of Autophagy‐Related …

SS Guo, XF Gao, YR Gu, ZX Wan, AM Lu… - Evidence‐Based …, 2016 - Wiley Online Library
Maca has been used as a foodstuff and a traditional medicine in the Andean region for over
2,000 years. Recently the neuroprotective effects of maca also arouse interest of …

Extract of Euryale ferox Salisb exerts antidepressant effects and regulates autophagy through the adenosine monophosphate‐activated protein kinase—UNC‐51‐like …

Z Huang, X Huang, Q Wang, R Jiang, G Sun, Y Xu… - IUBMB …, 2018 - Wiley Online Library
Positive regulation of autophagy by Euryale ferox Salisb (ES) leads to antidepressant
effects. This study focused on the potential antidepressant mechanisms induced by the …

Neuroprotective effects of macamide from maca (Lepidium meyenii Walp.) on corticosterone-induced hippocampal impairments through its anti-inflammatory …

Z Yu, D Li, S Zhai, H Xu, H Liu, M Ao, C Zhao, W Jin… - Food & Function, 2021 - pubs.rsc.org
The present study aims to investigate the protective effects of N-(3-methoxybenzyl)-(9Z, 12Z,
15Z)-octadecatrienamide (M 18: 3) on corticosterone-induced neurotoxicity. A neurotoxic …

The efficient synthesis and anti-fatigue activity evaluation of macamides: the unique bioactive compounds in Maca

T Liu, Z Peng, W Lai, Y Shao, Q Gao, M He, W Zhou… - Molecules, 2023 - mdpi.com
Macamides are a class of amide alkaloids that are only found in maca and are widely
considered to be its bioactive marker compounds. More than thirty macamide monomers …

Safety evaluation and protective effects of ethanolic extract from maca (Lepidium meyenii Walp.) against corticosterone and H2O2 induced neurotoxicity

Z Yu, W Jin, X Dong, M Ao, H Liu, L Yu - Regulatory Toxicology and …, 2020 - Elsevier
Maca has been traditionally used to enhance sexual behavior and fertility. Recently, maca's
neuroprotective effects have been reported. The purpose of this study was to investigate …