The evolution of AMPK and its homologs enabled exquisite responsivity and control of
cellular energetic homeostasis. Recent work has been critical in establishing the …

The AMPK (AMP-activated protein kinase) and TOR (target-of-rapamycin) pathways are
interlinked, opposing signaling pathways involved in sensing availability of nutrients and …

Since the discovery of AMP-activated protein kinase (AMPK) as a central regulator of energy
homeostasis, many exciting insights into its structure, regulation and physiological roles …

Long-chain fatty acids (LCFAs) play important roles in cellular energy metabolism, acting as
both an important energy source and signalling molecules. LCFA-CoA esters promote their …

Objective The AMP-activated protein kinase (AMPK) gets activated in response to energetic
stress such as contractions and plays a vital role in regulating various metabolic processes …

Skeletal muscle is one of the largest organs in the body and the largest protein repository.
Mitochondria are the main energy-producing organelles in cells and play an important role …

Meteorin‐like (metrnl) is a recently identified adipomyokine that beneficially affects glucose
metabolism; however, its underlying mechanism of action is not completely understood. We …

Current pharmacological treatments for bipolar disorder are inadequate and based on
serendipitously discovered drugs often with limited efficacy, burdensome side-effects, and …

5′-AMP-activated protein kinase (AMPK) plays diverse roles in various physiological and
pathological conditions. AMPK is involved in energy metabolism, which is perturbed by …

Abstract SNF1-related protein kinase 1 (SnRK1), the plant ortholog of mammalian AMP-
activated protein kinase/fungal (yeast) Sucrose Non-Fermenting 1 (AMPK/SNF1), plays a …