[HTML][HTML] National Institutes of Health Consensus Development Project on criteria for clinical trials in chronic graft-versus-host disease: I. The 2020 etiology and …

KM Williams, Y Inamoto, A Im, B Hamilton… - … and cellular therapy, 2021 - Elsevier
Preventing chronic graft-versus-host disease (GVHD) remains challenging because the
unique cellular and molecular pathways that incite chronic GVHD are poorly understood …

Graft-versus-host disease: a disorder of tissue regeneration and repair

R Chakraverty, T Teshima - Blood, The Journal of the American …, 2021 - ashpublications.org
Regenerative failure at barrier surfaces and maladaptive repair leading to fibrosis are
hallmarks of graft-versus-host disease (GVHD). Although immunosuppressive treatment can …

Peripheral helper-T-cell-derived CXCL13 is a crucial pathogenic factor in idiopathic multicentric Castleman disease

T Harada, Y Kikushige, T Miyamoto, K Uno… - Nature …, 2023 - nature.com
Castleman disease (CD) is a rare lymphoproliferative disorder. Among subtypes of CD,
idiopathic multicentric CD-not otherwise specified (iMCD-NOS) has a poor prognosis and its …

[HTML][HTML] Insights from integrating clinical and preclinical studies advance understanding of graft-versus-host disease

G Socié, LS Kean, R Zeiser… - The Journal of clinical …, 2021 - Am Soc Clin Investig
As a result of impressive increases in our knowledge of rodent and human immunology, the
understanding of the pathophysiologic mechanisms underlying graft-versus-host disease …

Controversies and expectations for the prevention of GVHD: a biological and clinical perspective

B Watkins, KM Williams - Frontiers in Immunology, 2022 - frontiersin.org
Severe acute and chronic graft versus host disease (GVHD) remains a major cause of
morbidity and mortality after allogeneic hematopoietic cell transplantation. Historically, cord …

Complex interactions of cellular players in chronic Graft-versus-Host Disease

LM Gail, KJ Schell, P Łacina, J Strobl… - Frontiers in …, 2023 - frontiersin.org
Chronic Graft-versus-Host Disease is a life-threatening inflammatory condition that affects
many patients after allogeneic hematopoietic stem cell transplantation. Although we have …

Developing role of B cells in the pathogenesis and treatment of chronic GVHD

X Li, Q Gao, Y Feng, X Zhang - British journal of haematology, 2019 - Wiley Online Library
Chronic graft‐versus‐host disease (cGVHD) is a major complication affecting the long‐term
survival of patients after allogeneic haematopoietic stem cell transplantation. The …

[HTML][HTML] Hematopoietic stem cell–derived Tregs are essential for maintaining favorable B cell lymphopoiesis following posttransplant cyclophosphamide

Y Sumii, T Kondo, S Ikegawa, T Fukumi, M Iwamoto… - JCI insight, 2023 - ncbi.nlm.nih.gov
Posttransplant cyclophosphamide (PTCy) is associated with a low incidence of chronic graft-
versus-host disease (cGVHD) following hematopoietic stem cell (HSC) transplantation …

Functional contributions of antigen presenting cells in chronic graft-versus-host disease

C Hong, R Jin, X Dai, X Gao - Frontiers in immunology, 2021 - frontiersin.org
Chronic graft-versus-host disease (cGVHD) is one of the most common reasons of late non-
relapse morbidity and mortality of patients with allogeneic hematopoietic stem cell …

Mangiferin promotes bregs level, activates Nrf2 antioxidant signaling, and inhibits proinflammatory cytokine expression in murine splenic mononuclear cells in vitro

Z Qin, J Ruan, M Lee, K Sun, P Chen, Y Chen… - Current Medical …, 2021 - Springer
Recent studies indicated that regulatory B cells (Bregs) and nuclear factor erythroid 2-
related factor 2 (Nrf2) antioxidant signaling pathway play important roles in the pathogenesis …