Intermittent hypoxic episodes in preterm infants: do they matter?

RJ Martin, K Wang, Ö Köroğlu, J Di Fiore, P Kc - Neonatology, 2011 - karger.com
Intermittent hypoxic episodes are typically a consequence of immature respiratory control
and remain a troublesome challenge for the neonatologist. Furthermore, their frequency and …

Continuous vital sign analysis for predicting and preventing neonatal diseases in the twenty-first century: big data to the forefront

N Kumar, G Akangire, B Sullivan, K Fairchild… - Pediatric …, 2020 - nature.com
In the neonatal intensive care unit (NICU), heart rate, respiratory rate, and oxygen saturation
are vital signs (VS) that are continuously monitored in infants, while blood pressure is often …

Oxygen saturation and outcomes in preterm infants

BOOST II United Kingdom, Australia, and … - … England Journal of …, 2013 - Mass Medical Soc
Background The clinically appropriate range for oxygen saturation in preterm infants is
unknown. Previous studies have shown that infants had reduced rates of retinopathy of …

Apnea of prematurity–perfect storm

JM Di Fiore, RJ Martin, EB Gauda - Respiratory physiology & neurobiology, 2013 - Elsevier
With increased survival of preterm infants as young as 23 weeks gestation, maintaining
adequate respiration and corresponding oxygenation represents a clinical challenge in this …

Clinical performance and safety of closed-loop systems: a systematic review and meta-analysis of randomized controlled trials

E Brogi, S Cyr, R Kazan, F Giunta… - Anesthesia & …, 2017 - journals.lww.com
METHODS We performed this review and meta-analysis following the Preferred Reporting
Items for Systematic Reviews and Meta-Analyses12 statements. We systematically explored …

Automated versus manual oxygen control with different saturation targets and modes of respiratory support in preterm infants

AH van Kaam, HD Hummler, M Wilinska… - The Journal of …, 2015 - Elsevier
Objective To determine the efficacy and safety of automated adjustment of the fraction of
inspired oxygen (FiO 2) in maintaining arterial oxygen saturation (SpO 2) within a higher …

Closed-loop automatic oxygen control (CLAC) in preterm infants: a randomized controlled trial

A Hallenberger, CF Poets, W Horn, A Seyfang… - …, 2014 - publications.aap.org
BACKGROUND AND OBJECTIVE: In preterm infants receiving supplemental oxygen,
routine manual control (RMC) of the fraction of inspired oxygen (Fio2) is often difficult and …

Oxygen saturation targeting in preterm infants receiving continuous positive airway pressure

K Lim, KI Wheeler, TJ Gale, HD Jackson… - The Journal of …, 2014 - Elsevier
Objective The precision of oxygen saturation (SpO 2) targeting in preterm infants on
continuous positive airway pressure (CPAP) is incompletely characterized. We therefore …

Automated versus manual control of inspired oxygen to target oxygen saturation in preterm infants: a systematic review and meta-analysis

S Mitra, B Singh, W El-Naggar, DD McMillan - Journal of Perinatology, 2018 - nature.com
Objectives To conduct a systematic review of clinical trials comparing automated versus
manual fraction of inspired oxygen (FiO2) control to target oxygen saturation (SpO2) in …

Retinopathy of prematurity: therapeutic strategies based on pathophysiology

R Cayabyab, R Ramanathan - Neonatology, 2016 - karger.com
Retinopathy of prematurity (ROP) continues to be a major preventable cause of blindness
and visual handicaps globally. With improved perinatal care, improved survival of …