Accumulating evidence points to the causal role of triglyceride-rich lipoproteins and their
cholesterol-enriched remnants in atherogenesis. Genetic studies in particular have not only …

Despite the success of LDL-lowering drugs in reducing cardiovascular disease (CVD), there
remains a large burden of residual disease due in part to persistent dyslipidemia …

In the mammalian lung, an apparently homogenous mesh of capillary vessels surrounds
each alveolus, forming the vast respiratory surface across which oxygen transfers to the …

Lipoprotein lipase (LPL) is one of the most important factors in systemic lipid partitioning and
metabolism. It mediates intravascular hydrolysis of triglycerides packed in lipoproteins such …

Our understanding of the role of the vascular endothelium has evolved over the past 2
decades, with the recognition that it is a dynamically regulated organ and that it plays a …

The enzyme lipoprotein lipase (LPL), originally identified as the clearing factor lipase,
hydrolyzes triglycerides present in the triglyceride-rich lipoproteins VLDL and chylomicrons …

Abstract In mammals, triglyceride (TG), the main form of lipids for storing and providing
energy, is stored in white adipose tissue (WAT) after food intake, while during fasting it is …

Triglyceride-rich lipoproteins deliver fatty acids to tissues for oxidation and for storage.
Release of fatty acids from circulating lipoprotein triglycerides is carried out by lipoprotein …

Abstract Apolipoprotein C-II (apoC-II) is a small exchangeable apolipoprotein found on
triglyceride-rich lipoproteins (TRL), such as chylomicrons (CM) and very low-density …

The key initiating process in atherogenesis is the subendothelial retention of apolipoprotein
B–containing lipoproteins. Local biological responses to these retained lipoproteins …