Coronary heart disease (CHD) is the single largest cause of death in the developed
countries and is one of the leading causes of disease burden in developing countries. In …

The term acute coronary syndrome (ACS) refers to any group of clinical symptoms
compatible with acute myocardial ischemia and includes unstable angina (UA), non—ST …

Document Reviewers: Sigmund Silber (CPG Review Coordinator)(Germany), Frank V.
Aguirre (USA), Nawwar Al-Attar (France), Eduardo Alegria (Spain), Felicita Andreotti (Italy) …

Background Angiotensin-converting–enzyme (ACE) inhibitors such as captopril reduce
mortality and cardiovascular morbidity among patients with myocardial infarction …

Background Despite improvements in the emergency treatment of myocardial infarction (MI),
early mortality and morbidity remain high. The antiplatelet agent clopidogrel adds to the …

Background Treatment with angiotensin-converting–enzyme (ACE) inhibitors reduces
mortality among survivors of acute myocardial infarction, but whether to use ACE inhibitors …

The management of acute myocardial infarction continues to undergo major changes. Good
practice should be based on sound evidence derived from well-conducted clinical trials …

Background Despite previous randomised trials of early β-blocker therapy in the emergency
treatment of myocardial infarction (MI), uncertainty has persisted about the value of adding it …

Background We quantified cardiovascular death and/or left ventricular (LV) dilatation in
patients from the SAVE trial to determine whether dilatation continued beyond 1 year …

The renin-angiotensin system plays a major role in cardiovascular disease and during the
past decade extensive research investigated the possible clinical benefit of the use of …