Importance Approximately 0.5% to 3% of patients undergoing surgery will experience
infection at or adjacent to the surgical incision site. Compared with patients undergoing …

Periprosthetic joint infections are a devastating complication after arthroplasty and are
associated with substantial patient morbidity. More than 25% of revisions are attributed to …

Importance The benefits of antimicrobial prophylaxis are limited to the first 24 hours
postoperatively. Little is known about the harms associated with continuing antimicrobial …

Background A reported penicillin allergy may compromise receipt of recommended
antibiotic prophylaxis intended to prevent surgical site infections (SSIs). Most patients with a …

Importance Inappropriate antimicrobial drug use is associated with adverse events in
hospitalized patients and contributes to the emergence and spread of resistant pathogens …

Importance Previous studies suggested that a bundled intervention was associated with
lower rates ofStaphylococcus aureussurgical site infections (SSIs) among patients having …

Importance Despite improvements in perioperative mortality, the incidence of postoperative
surgical site infection (SSI) remains high after pancreatoduodenectomy. The effect of broad …

Hip fractures cause significant morbidity and are associated with increased mortality.
Women experience 80% of hip fractures, and the average age of persons who have a hip …

Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant
postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality …

Background: There is a growing concern for microbial resistance as a result of overuse of
antibiotics. Although guidelines have focused on the use of antibiotics for surgery in general …