Deep brain stimulation has been extensively studied as a therapeutic option for treatment-
resistant depression (TRD). DBS across different targets is associated with on average 60 …

Deep brain stimulation is a promising therapeutic approach for patients with treatment-
resistant obsessive-compulsive disorder, a condition linked to abnormalities in corticobasal …

Short-and long-term antidepressant effects of deep brain stimulation (DBS) in treatment-
resistant depression (TRD) have been demonstrated for several brain targets in open-label …

At the group-level, deep brain stimulation leads to significant therapeutic benefit in a
multitude of neurological and neuropsychiatric disorders. At the single-patient level …

Humans have lived in a dynamic environment fraught with potential dangers for thousands
of years. While fear and stress were crucial for the survival of our ancestors, today, they are …

Introduction Deep brain stimulation alleviates tremor of various origins. The dentato-rubro-
thalamic tract (DRT) has been suspected as a common tremor-reducing structure. Statistical …

The medial forebrain bundle—a white matter pathway projecting from the ventral tegmental
area—is a structure that has been under a lot of scrutinies recently due to its implications in …

The brain hemispheres can be divided into an upper dorsal and a lower ventral system.
Each system consists of distinct cortical regions connected via long association tracts. The …

In the central nervous system (CNS), dopamine (DA) is involved in motor and cognitive
functions. Although the cerebellum is not been considered an elective dopaminergic region …

Subthalamic deep brain stimulation (STN-DBS) for Parkinson's disease treats motor
symptoms and improves quality of life, but can be complicated by adverse neuropsychiatric …