[HTML][HTML] Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration

DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy

GH Nam, Y Choi, GB Kim, S Kim, SA Kim… - Advanced …, 2020 - Wiley Online Library
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …

DNA in extracellular vesicles: biological and clinical aspects

J Elzanowska, C Semira, B Costa‐Silva - Molecular Oncology, 2021 - Wiley Online Library
The study of extracellular vesicles (EVs), especially in the liquid biopsy field, has rapidly
evolved in recent years. However, most EV studies have focused on RNA or protein content …

[HTML][HTML] Immune response following traumatic spinal cord injury: Pathophysiology and therapies

RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

[HTML][HTML] The evolving landscape of exosomes in neurodegenerative diseases: exosomes characteristics and a promising role in early diagnosis

S Rastogi, V Sharma, PS Bharti, K Rani… - International journal of …, 2021 - mdpi.com
Neurodegenerative diseases (ND) remains to be one of the biggest burdens on healthcare
systems and serves as a leading cause of disability and death. Alzheimer's disease (AD) is …

[HTML][HTML] Multi-omics analysis of microglial extracellular vesicles from human Alzheimer's disease brain tissue reveals disease-associated signatures

W Cohn, M Melnik, C Huang, B Teter… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of dementia, yet there is no cure or
diagnostics available prior to the onset of clinical symptoms. Extracellular vesicles (EVs) are …

[HTML][HTML] Microglia in aging and Alzheimer's disease: a comparative species review

MK Edler, I Mhatre-Winters, JR Richardson - Cells, 2021 - mdpi.com
Microglia are the primary immune cells of the central nervous system that help nourish and
support neurons, clear debris, and respond to foreign stimuli. Greatly impacted by their …

[HTML][HTML] Circulating exosomal miRNA as diagnostic biomarkers of neurodegenerative diseases

L Wang, L Zhang - Frontiers in molecular neuroscience, 2020 - frontiersin.org
Neurodegenerative diseases (NDDs) are a group of diseases caused by chronic and
progressive degeneration of neural tissue. The main pathological manifestations are …

[HTML][HTML] Exosomal RNAs: novel potential biomarkers for diseases—a review

J Wang, BL Yue, YZ Huang, XY Lan, WJ Liu… - International Journal of …, 2022 - mdpi.com
Exosomes are a subset of nano-sized extracellular vesicles originating from endosomes.
Exosomes mediate cell-to-cell communication with their cargos, which includes mRNAs …

Extracellular vesicles as an emerging frontier in spinal cord injury pathobiology and therapy

D Dutta, N Khan, J Wu, SM Jay - Trends in neurosciences, 2021 - cell.com
Extracellular vesicles (EVs) are membrane-delimited particles that are secreted by nearly all
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …