[HTML][HTML] DNA vaccines: prime time is now

EN Gary, DB Weiner - Current Opinion in Immunology, 2020 - Elsevier
Recently newer synthetic DNA vaccines have been rapidly advanced to clinical study and
have demonstrated an impressive degree of immune potency and tolerability. Improvements …

[HTML][HTML] Current status of Zika virus vaccines: successes and challenges

A Pattnaik, BR Sahoo, AK Pattnaik - Vaccines, 2020 - mdpi.com
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …

[HTML][HTML] Sexual transmission of Zika virus and other flaviviruses: a living systematic review

MJ Counotte, CR Kim, J Wang, K Bernstein… - PLoS …, 2018 - journals.plos.org
Background Health authorities in the United States and Europe reported an increasing
number of travel-associated episodes of sexual transmission of Zika virus (ZIKV) following …

Viral threat to male fertility

W Liu, R Han, H Wu, D Han - Andrologia, 2018 - Wiley Online Library
The detrimental effects of Zika virus (ZIKV) infection on mouse testicular functions have
reminded a viral threat to male fertility. A broad range of virus families has tropism for male …

Zika vaccine development: current status

GA Poland, IG Ovsyannikova, RB Kennedy - Mayo Clinic Proceedings, 2019 - Elsevier
Zika virus outbreaks have been explosive and unpredictable and have led to significant
adverse health effects—as well as considerable public anxiety. Significant scientific work …

[HTML][HTML] A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

C Shan, AE Muruato, BW Jagger, J Richner… - Nature …, 2017 - nature.com
Zika virus infection during pregnancy can cause congenital abnormities or fetal demise. The
persistence of Zika virus in the male reproductive system poses a risk of sexual …

From ancient to emerging infections: the odyssey of viruses in the male genital tract

A Le Tortorec, G Matusali, D Mahé… - Physiological …, 2020 - journals.physiology.org
The male genital tract (MGT) is the target of a number of viral infections that can have
deleterious consequences at the individual, offspring, and population levels. These …

Durability and correlates of vaccine protection against Zika virus in rhesus monkeys

P Abbink, RA Larocca, K Visitsunthorn… - Science translational …, 2017 - science.org
An effective Zika virus (ZIKV) vaccine will require long-term durable protection. Several ZIKV
vaccine candidates have demonstrated protective efficacy in nonhuman primates, but these …

Zika virus vaccine development: progress in the face of new challenges

MS Diamond, JE Ledgerwood… - Annual review of …, 2019 - annualreviews.org
Zika virus (ZIKV) emerged at a global level when it spread to the Americas and began
causing congenital malformations and microcephaly in 2015. A rapid response by …

[HTML][HTML] Zika virus infects human testicular tissue and germ cells

G Matusali, L Houzet, AP Satie, D Mahé… - The Journal of …, 2018 - Am Soc Clin Investig
Zika virus (ZIKV) is a teratogenic mosquito-borne flavivirus that can be sexually transmitted
from man to woman. The finding of high viral loads and prolonged viral shedding in semen …