[HTML][HTML] DNA vaccines: prime time is now
EN Gary, DB Weiner - Current Opinion in Immunology, 2020 - Elsevier
Recently newer synthetic DNA vaccines have been rapidly advanced to clinical study and
have demonstrated an impressive degree of immune potency and tolerability. Improvements …
have demonstrated an impressive degree of immune potency and tolerability. Improvements …
[HTML][HTML] Current status of Zika virus vaccines: successes and challenges
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
[HTML][HTML] Sexual transmission of Zika virus and other flaviviruses: a living systematic review
MJ Counotte, CR Kim, J Wang, K Bernstein… - PLoS …, 2018 - journals.plos.org
Background Health authorities in the United States and Europe reported an increasing
number of travel-associated episodes of sexual transmission of Zika virus (ZIKV) following …
number of travel-associated episodes of sexual transmission of Zika virus (ZIKV) following …
Viral threat to male fertility
W Liu, R Han, H Wu, D Han - Andrologia, 2018 - Wiley Online Library
The detrimental effects of Zika virus (ZIKV) infection on mouse testicular functions have
reminded a viral threat to male fertility. A broad range of virus families has tropism for male …
reminded a viral threat to male fertility. A broad range of virus families has tropism for male …
Zika vaccine development: current status
GA Poland, IG Ovsyannikova, RB Kennedy - Mayo Clinic Proceedings, 2019 - Elsevier
Zika virus outbreaks have been explosive and unpredictable and have led to significant
adverse health effects—as well as considerable public anxiety. Significant scientific work …
adverse health effects—as well as considerable public anxiety. Significant scientific work …
[HTML][HTML] A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
Zika virus infection during pregnancy can cause congenital abnormities or fetal demise. The
persistence of Zika virus in the male reproductive system poses a risk of sexual …
persistence of Zika virus in the male reproductive system poses a risk of sexual …
From ancient to emerging infections: the odyssey of viruses in the male genital tract
A Le Tortorec, G Matusali, D Mahé… - Physiological …, 2020 - journals.physiology.org
The male genital tract (MGT) is the target of a number of viral infections that can have
deleterious consequences at the individual, offspring, and population levels. These …
deleterious consequences at the individual, offspring, and population levels. These …
Durability and correlates of vaccine protection against Zika virus in rhesus monkeys
P Abbink, RA Larocca, K Visitsunthorn… - Science translational …, 2017 - science.org
An effective Zika virus (ZIKV) vaccine will require long-term durable protection. Several ZIKV
vaccine candidates have demonstrated protective efficacy in nonhuman primates, but these …
vaccine candidates have demonstrated protective efficacy in nonhuman primates, but these …
Zika virus vaccine development: progress in the face of new challenges
MS Diamond, JE Ledgerwood… - Annual review of …, 2019 - annualreviews.org
Zika virus (ZIKV) emerged at a global level when it spread to the Americas and began
causing congenital malformations and microcephaly in 2015. A rapid response by …
causing congenital malformations and microcephaly in 2015. A rapid response by …
[HTML][HTML] Zika virus infects human testicular tissue and germ cells
G Matusali, L Houzet, AP Satie, D Mahé… - The Journal of …, 2018 - Am Soc Clin Investig
Zika virus (ZIKV) is a teratogenic mosquito-borne flavivirus that can be sexually transmitted
from man to woman. The finding of high viral loads and prolonged viral shedding in semen …
from man to woman. The finding of high viral loads and prolonged viral shedding in semen …