Dendritic cells (DCs) are professional antigen-presenting cells that play a key role in
shaping adaptive immunity. DCs have a unique ability to sample their environment, capture …

The dynamic and reversible modification of nuclear and cytoplasmic proteins by O-
GlcNAcylation significantly impacts the function and dysfunction of the immune system. O …

Rotator cuff injury (RCI) is a common musculoskeletal problem that can have a significant
impact on the quality of life and functional abilities of those affected. Novel therapies …

A pleiotropic immunoregulatory cytokine, TGF-β, signals via the receptor-regulated SMADs:
SMAD2 and SMAD3, which are constitutively expressed in normal cells. Here, we show that …

CD8+ T cells are essential for adaptive immunity against infection and tumors. Their ability to
proliferate after stimulation is crucial to their functionality. Dendritic cells (DCs) are …

Dendritic cells (DCs) serve as professional antigen-presenting cells (APC) bridging innate
and adaptive immunity, playing an essential role in triggering specific cellular and humoral …

This research investigates the regulatory role of the transcription factor PU. 1 in type 1
conventional dendritic cells (cDC1) and its therapeutic potential of modulating the nuclear …

Immunotherapy using dendritic cell-based vaccination is a natural approach using the
capabilities and functions inherent in the patient's immune system to eliminate tumor cells …

Objective Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease. The
immune imbalance of T cells is an essential pathological mechanism of ITP, more specific …

Allergic asthma is an increasing burden in industrialized countries, where treatments are
limited to treating symptoms rather than root causes. In recent years, the use of inhaled …