Investigating the importance of EGFR (− 216G/T), Exo1 (K589E) and LEP (− 2548G/A) gene polymorphisms with risk of lung cancer as potential diagnostic biomarker …
M Pezeshki, SM Hosseini, J Ansari… - Egyptian Journal of …, 2023 - Springer
Abstract Background In Iran, lung cancer is the third most common type of cancer and its
prevalence is increasing rapidly. Identification informative genetic polymorphisms in cancer …
prevalence is increasing rapidly. Identification informative genetic polymorphisms in cancer …
Associations between Nine Polymorphisms in EXO1 and Cancer Susceptibility: A Systematic Review and Meta-Analysis of 39 Case-control Studies
M Zhang, D Zhao, C Yan, L Zhang, C Liang - Scientific reports, 2016 - nature.com
An increasing number of studies have highlighted the potential link between EXO1
polymorphisms and cancer risk, although no consensus has yet been obtained. Thus, we …
polymorphisms and cancer risk, although no consensus has yet been obtained. Thus, we …
EXO1 overexpression is associated with poor prognosis of hepatocellular carcinoma patients
Y Dai, Z Tang, Z Yang, L Zhang, Q Deng, X Zhang… - Cell Cycle, 2018 - Taylor & Francis
The roles of exonuclease 1 (EXO1) in hepatocellular carcinoma (HCC) tumorigenesis and
progression remain unclear. This study aimed to assess the prognostic value and …
progression remain unclear. This study aimed to assess the prognostic value and …
Breast tumors with elevated expression of 1q candidate genes confer poor clinical outcome and sensitivity to Ras/PI3K inhibition
M Muthuswami, V Ramesh, S Banerjee… - PloS one, 2013 - journals.plos.org
Genomic aberrations are common in cancers and the long arm of chromosome 1 is known
for its frequent amplifications in breast cancer. However, the key candidate genes of 1q, and …
for its frequent amplifications in breast cancer. However, the key candidate genes of 1q, and …
[HTML][HTML] Elevated EXO1 expression is associated with breast carcinogenesis and poor prognosis
J Liu, J Zhang - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Background Breast cancer is the most common cancer and leading cause of cancer
mortality in women worldwide. Exonuclease 1 (EXO1), a protein with 5'to 3'exonuclease and …
mortality in women worldwide. Exonuclease 1 (EXO1), a protein with 5'to 3'exonuclease and …
[HTML][HTML] EXO1 plays a carcinogenic role in hepatocellular carcinoma and is related to the regulation of FOXP3
G Yang, K Dong, Z Zhang, E Zhang, B Liang… - Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Exonuclease 1 (EXO1), a member of the RAD2 nuclease family, was first described
as possessing 5'to 3'nuclease activity and 5'structure-specific endonuclease activity. Here …
as possessing 5'to 3'nuclease activity and 5'structure-specific endonuclease activity. Here …
Multi-functions of exonuclease 1 in DNA damage response and cancer susceptibility
S Yan, S Gao, P Zhou - Radiation Medicine and Protection, 2021 - mednexus.org
Exonuclease 1 (EXO1) can catalyze nucleotide chain excision with its conserved N-terminal
domain of 5′ to 3′ exonuclease activity, enabling it to influence diverse biological …
domain of 5′ to 3′ exonuclease activity, enabling it to influence diverse biological …
[HTML][HTML] Mutations in known and novel cancer susceptibility genes in young patients with pancreatic cancer
S Alimirzaie, A Mohamadkhani, S Masoudi… - Archives of Iranian …, 2018 - journalaim.com
Background: Pancreatic cancer is the fourth most common cause of mortality due to cancer,
globally. It has a poor prognosis and is usually diagnosed at later stages when tumor …
globally. It has a poor prognosis and is usually diagnosed at later stages when tumor …
Multiple hits for the association of uterine fibroids on human chromosome 1q43
Uterine leiomyomas (or fibroids) are the most common tumors in women of reproductive
age. Early studies of two familial cancer syndromes, the multiple cutaneous and uterine …
age. Early studies of two familial cancer syndromes, the multiple cutaneous and uterine …
Genetic polymorphisms in CDH1 and Exo1 genes elevate the prostate cancer risk in Bangladeshi population
H Imtiaz, S Afroz, MA Hossain, SF Bellah… - Tumor …, 2019 - journals.sagepub.com
The polymorphisms of invasion suppressor gene CDH1 and DNA mismatch repair gene
Exo1 have been reported to play critical role in the development, tumorigenesis, and …
Exo1 have been reported to play critical role in the development, tumorigenesis, and …