Thyroid surgery for differentiated thyroid cancer—recent advances and future directions
Population-based studies have demonstrated that an increasing number of incidental
thyroid nodules are being identified. The corresponding increase in thyroid-based …
thyroid nodules are being identified. The corresponding increase in thyroid-based …
Cost-effectiveness of precision medicine: a scoping review
M Kasztura, A Richard, NE Bempong, D Loncar… - International journal of …, 2019 - Springer
Objectives Precision medicine (PM) aims to improve patient outcomes by stratifying or
individualizing diagnosis and treatment decisions. Previous reviews found inconclusive …
individualizing diagnosis and treatment decisions. Previous reviews found inconclusive …
The American Association of Endocrine Surgeons guidelines for the definitive surgical management of thyroid disease in adults
KN Patel, L Yip, CC Lubitz, EG Grubbs, BS Miller… - Annals of …, 2020 - journals.lww.com
Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …
thyroidectomy. Background: Surgical management of thyroid disease has evolved …
Thyroid nodules: Global, economic, and personal burdens
Thyroid nodules have garnered attention due to changes in population surveillance systems
and rising concerns about the associated financial burden on healthcare systems, payers …
and rising concerns about the associated financial burden on healthcare systems, payers …
Molecular testing versus diagnostic lobectomy in Bethesda III/IV thyroid nodules: a cost-effectiveness analysis
Background: Molecular tests (MT) using gene expression and/or mutational analysis have
been developed to reduce the need for diagnostic surgery for indeterminate (Bethesda III/IV) …
been developed to reduce the need for diagnostic surgery for indeterminate (Bethesda III/IV) …
[18F]FDG-PET/CT to prevent futile surgery in indeterminate thyroid nodules: a blinded, randomised controlled multicentre trial
EJ de Koster, LF de Geus-Oei, AH Brouwers… - European Journal of …, 2022 - Springer
Purpose To assess the impact of an [18 F] FDG-PET/CT-driven diagnostic workup to rule out
malignancy, avoid futile diagnostic surgeries, and improve patient outcomes in thyroid …
malignancy, avoid futile diagnostic surgeries, and improve patient outcomes in thyroid …
The role of molecular testing for the indeterminate thyroid FNA
ED Rossi, L Pantanowitz, WC Faquin - Genes, 2019 - mdpi.com
Thyroid nodules are common in the adult population where a majority are benign and only
4.0% to 6.5% are malignant. Fine needle aspiration (FNA) is a key method used in the early …
4.0% to 6.5% are malignant. Fine needle aspiration (FNA) is a key method used in the early …
Thyroid nodule molecular testing: is it ready for prime time?
TM Khan, MA Zeiger - Frontiers in Endocrinology, 2020 - frontiersin.org
Cytologically indeterminate thyroid nodules remain a diagnostic and clinical challenge, and
molecular testing has been advocated and advanced as a diagnostic modality to help guide …
molecular testing has been advocated and advanced as a diagnostic modality to help guide …
The effect modification of ultrasound risk classification on molecular testing in predicting the risk of malignancy in cytologically indeterminate thyroid nodules
TX Hu, DT Nguyen, M Patel, K Beckett, M Douek… - Thyroid, 2022 - liebertpub.com
Background: Thyroid nodules with indeterminate cytology are increasingly subjected to
molecular testing. We evaluated the diagnostic performances of Afirma Genomic …
molecular testing. We evaluated the diagnostic performances of Afirma Genomic …
A machine-learning algorithm for distinguishing malignant from benign indeterminate thyroid nodules using ultrasound radiomic features
Background: Ultrasound (US)-guided fine needle aspiration (FNA) cytology is the gold
standard for the evaluation of thyroid nodules. However, up to 30% of FNA results are …
standard for the evaluation of thyroid nodules. However, up to 30% of FNA results are …