Multiphysics microfluidics for cell manipulation and separation: a review

H Cha, H Fallahi, Y Dai, D Yuan, H An, NT Nguyen… - Lab on a Chip, 2022 - pubs.rsc.org
Multiphysics microfluidics, which combines multiple functional physical processes in a
microfluidics platform, is an emerging research area that has attracted increasing interest for …

Coupling of mechanical deformation and electromagnetic fields in biological cells

M Torbati, K Mozaffari, L Liu, P Sharma - Reviews of Modern Physics, 2022 - APS
The cell, as the most fundamental unit of life, is a microcosm of biology in which the
confluence of nearly all aspects of classical physics (mechanics, statistical physics …

Dielectrophoresis: From molecular to micrometer-scale analytes

D Kim, M Sonker, A Ros - Analytical chemistry, 2018 - ACS Publications
The complexity of biological analytes demands powerful analysis techniques in order to
reveal cellular processes and pathways on the molecular level. 1 Thus, ever refining …

Tuning particle inertial separation in sinusoidal channels by embedding periodic obstacle microstructures

H Cha, H Fallahi, Y Dai, S Yadav, S Hettiarachchi… - Lab on a Chip, 2022 - pubs.rsc.org
Inertial microfluidics functions solely based on the fluid dynamics at relatively high flow
speed. Thus, channel geometry is the critical design parameter that contributes to the …

Microsphere mediated exosome isolation and ultra-sensitive detection on a dielectrophoresis integrated microfluidic device

W Zhao, L Zhang, Y Ye, Y Li, X Luan, J Liu, J Cheng… - Analyst, 2021 - pubs.rsc.org
Tumor-derived exosomes have been recognized as potential biomarkers for cancer
diagnosis because they are actively involved in cancer progression and metastasis …

Liquid biopsy: one cell at a time

SB Lim, W Di Lee, J Vasudevan, WT Lim… - NPJ precision …, 2019 - nature.com
As an alternative target to surgically resected tissue specimens, liquid biopsy has gained
much attention over the past decade. Of the various circulating biomarkers, circulating tumor …

Recent advances in microfluidic platform for physical and immunological detection and capture of circulating tumor cells

MP Bhat, V Thendral, UT Uthappa, KH Lee, M Kigga… - Biosensors, 2022 - mdpi.com
CTCs (circulating tumor cells) are well-known for their use in clinical trials for tumor
diagnosis. Capturing and isolating these CTCs from whole blood samples has enormous …

[HTML][HTML] Electrified lab on disc systems: A comprehensive review on electrokinetic applications

V Kordzadeh-Kermani, M Madadelahi… - Biosensors and …, 2022 - Elsevier
Many advanced microfluidic Lab-on-disc (LOD) devices require an on-board power supply
for powering active components. LODs with an on-board electrical power supply are called …

Signal-based methods in dielectrophoresis for cell and particle separation

M Farasat, E Aalaei, S Kheirati Ronizi, A Bakhshi… - Biosensors, 2022 - mdpi.com
Separation and detection of cells and particles in a suspension are essential for various
applications, including biomedical investigations and clinical diagnostics. Microfluidics …

Microfluidic strategies for label-free exosomes isolation and analysis

W Su, H Li, W Chen, J Qin - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Exosomes are nanoscale membrane vesicles (∼ 30–150 nm) actively released by most
types of cells, which has great potential for non-invasive disease diagnostics. Current …