Cardiotoxicity of anticancer drugs: Molecular mechanisms and strategies for cardioprotection
MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …
oncology patients. However, these antineoplastic treatments may also induce adverse …
Remote ischaemic conditioning: defining critical criteria for success—report from the 11th Hatter Cardiovascular Workshop
Abstract The Hatter Cardiovascular Institute biennial workshop, originally scheduled for April
2020 but postponed for 2 years due to the Covid pandemic, was organised to debate and …
2020 but postponed for 2 years due to the Covid pandemic, was organised to debate and …
[HTML][HTML] PHB2 ameliorates Doxorubicin-induced cardiomyopathy through interaction with NDUFV2 and restoration of mitochondrial complex I function
M Yang, M Abudureyimu, X Wang, Y Zhou, Y Zhang… - Redox biology, 2023 - Elsevier
Background Doxorubicin (DOX) is among the most widely employed antitumor agents,
although its clinical applications have been largely hindered by severe cardiotoxicity. Earlier …
although its clinical applications have been largely hindered by severe cardiotoxicity. Earlier …
Current status of experimental animal skin flap models: ischemic preconditioning and molecular factors
JH Lee, HJ You, TY Lee, HJ Kang - International journal of molecular …, 2022 - mdpi.com
Skin flaps are necessary in plastic and reconstructive surgery for the removal of skin cancer,
wounds, and ulcers. A skin flap is a portion of skin with its own blood supply that is partially …
wounds, and ulcers. A skin flap is a portion of skin with its own blood supply that is partially …
Yellow wine polyphenolic compound protects against doxorubicin-induced cardiotoxicity by modulating the composition and metabolic function of the gut microbiota
H Lin, L Meng, Z Sun, S Sun, X Huang, N Lin… - Circulation: Heart …, 2021 - Am Heart Assoc
Background: Dietary polyphenols help to prevent cardiovascular diseases, and interactions
between polyphenols and gut microbiota are known to exist. In this study, we speculated that …
between polyphenols and gut microbiota are known to exist. In this study, we speculated that …
Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4-dependent mechanism
P Szczepaniak, M Siedlinski… - The Journal of …, 2022 - Am Soc Clin Investig
Cardiovascular disease is the major cause of morbidity and mortality in breast cancer
survivors. Chemotherapy contributes to this risk. We aimed to define the mechanisms of long …
survivors. Chemotherapy contributes to this risk. We aimed to define the mechanisms of long …
Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review
FN Salloum, CG Tocchetti, P Ameri, H Ardehali… - Cardio Oncology, 2023 - jacc.org
Despite improvements in cancer survival, cancer therapy–related cardiovascular toxicity has
risen to become a prominent clinical challenge. This has led to the growth of the burgeoning …
risen to become a prominent clinical challenge. This has led to the growth of the burgeoning …
Cardiovascular disease in adult cancer survivors: a review of current evidence, strategies for prevention and management, and future directions for cardio-oncology
Abstract Purpose of Review Cardiovascular disease is long-term complication of both
cancer and anti-cancer treatment and can have significant ramifications for health-related …
cancer and anti-cancer treatment and can have significant ramifications for health-related …
Recent advances in mitochondrial fission/fusion-targeted therapy in doxorubicin-induced cardiotoxicity
Doxorubicin (DOX) has been recognized as one of the most effective chemotherapies and
extensively used in the clinical settings of human cancer. However, DOX-mediated …
extensively used in the clinical settings of human cancer. However, DOX-mediated …
Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart
We review some of the important discoveries and advances made in basic and translational
cardiac research in 2020. For example, in the field of myocardial infarction (MI), new aspects …
cardiac research in 2020. For example, in the field of myocardial infarction (MI), new aspects …