Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

R Sartori, V Romanello, M Sandri - Nature communications, 2021 - nature.com
Skeletal muscle is the protein reservoir of our body and an important regulator of glucose
and lipid homeostasis. Consequently, the growth or the loss of muscle mass can influence …

Signaling pathways that control muscle mass

A Vainshtein, M Sandri - International journal of molecular sciences, 2020 - mdpi.com
The loss of skeletal muscle mass under a wide range of acute and chronic maladies is
associated with poor prognosis, reduced quality of life, and increased mortality. Decades of …

Functions and regulatory mechanisms of lncRNAs in skeletal myogenesis, muscle disease and meat production

S Wang, J Jin, Z Xu, B Zuo - Cells, 2019 - mdpi.com
Myogenesis is a complex biological process, and understanding the regulatory network of
skeletal myogenesis will contribute to the treatment of human muscle related diseases and …

[HTML][HTML] Non-coding RNA basis of muscle atrophy

Q Liu, J Deng, Y Qiu, J Gao, J Li, L Guan, H Lee… - … Therapy-Nucleic Acids, 2021 - cell.com
Muscle atrophy is a common complication of many chronic diseases including heart failure,
cancer cachexia, aging, etc. Unhealthy habits and usage of hormones such as …

Involvements of long noncoding RNAs in obesity‐associated inflammatory diseases

SN Wijesinghe, T Nicholson, K Tsintzas… - Obesity …, 2021 - Wiley Online Library
Obesity is associated with chronic low‐grade inflammation that affects the phenotype of
multiple tissues and therefore is implicated in the development and progression of several …

The functional role of long non-coding RNA in myogenesis and skeletal muscle atrophy

K Hitachi, M Honda, K Tsuchida - Cells, 2022 - mdpi.com
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis.
Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass …

Role of MicroRNAs and long non-coding RNAs in sarcopenia

J Lee, H Kang - Cells, 2022 - mdpi.com
Sarcopenia is an age-related pathological process characterized by loss of muscle mass
and function, which consequently affects the quality of life of the elderly. There is growing …

A multi-tissue multi-omics analysis reveals distinct kineztics in entrainment of diurnal transcriptomes by inverted feeding

H Xin, F Deng, M Zhou, R Huang, X Ma, H Tian, Y Tan… - Iscience, 2021 - cell.com
Time of eating synchronizes circadian rhythms of metabolism and physiology. Inverted
feeding can uncouple peripheral circadian clocks from the central clock located in the …

Uremic sarcopenia: clinical evidence and basic experimental approach

H Nishi, K Takemura, T Higashihara, R Inagi - Nutrients, 2020 - mdpi.com
Sustained physical activity extends healthy life years while a lower activity due to sarcopenia
can reduce them. Sarcopenia is defined as a decrease in skeletal muscle mass and strength …

The function of LncRNA-H19 in cardiac hypertrophy

W Su, Q Huo, H Wu, L Wang, X Ding, L Liang, L Zhou… - Cell & bioscience, 2021 - Springer
Cardiac hypertrophy, characterized by the enlargement of cardiomyocytes, is initially an
adaptive response to physiological and pathological stimuli. Decompensated cardiac …