Leveraging cellular mechano-responsiveness for cancer therapy

J Hyun, HW Kim - Trends in Molecular Medicine, 2022 - cell.com
Cells sense the biophysical properties of the tumor microenvironment (TME) and adopt
these signals in their development, progression, and metastatic dissemination. Recent work …

Three Component One-Pot Synthesis and Antiproliferative Activity of New [1,2,4]Triazolo[4,3-a]pyrimidines

M Ben Hassen, D Msalbi, B Jismy, F Elghali, S Aifa… - Molecules, 2023 - mdpi.com
A series of new [1, 2, 4] triazolo [4, 3-a] pyrimidine derivatives was prepared using a one-pot
three-component synthesis from 5-amino-1-phenyl-1 H-1, 2, 4-triazoles, aromatic aldehydes …

Fatty acid-binding protein 5 is a functional biomarker and indicator of ferroptosis in cerebral hypoxia

H Peng, S Xin, S Pfeiffer, C Müller, J Merl-Pham… - Cell Death & …, 2024 - nature.com
The progression of human degenerative and hypoxic/ischemic diseases is accompanied by
widespread cell death. One death process linking iron-catalyzed reactive species with lipid …

[HTML][HTML] Synergistic effects of combined cisplatin and Clinacanthus nutans extract on triple negative breast cancer cells

NFABA Bakar, ZL Yeo, F Hussin… - Journal of Taibah …, 2023 - ncbi.nlm.nih.gov
Objective Triple negative breast cancer (TNBC) is the most invasive breast cancer subtype
enriched with cancer stem cells. TNBCs do not express estrogen, progesterone, or human …

Study on inhibitory effects of AsA, ZnCl 2, and BAPTA-AM on Cd 2+-induced cell oxidative stress and cytotoxicity by scanning electrochemical microscopy (SECM) …

K Gao, Y Du, N Pan, X Zhou, L Lu, X Wang - Sensors & Diagnostics, 2024 - pubs.rsc.org
Cadmium (Cd) can cause cell oxidative stress and cytotoxicity. Few studies have focused on
inhibitory effects on Cd2+-induced oxidative stress and related cytotoxicity. Scanning …

Structural and Biophysical Investigation of Calmodulin Binding to the Third Domain of Human Prp40a

BJ Ferrer - 2022 - search.proquest.com
Human Pre-mRNA-processing factor 40 homolog A (hPrp40A) is a splicing factor that
interacts with the Huntington's Disease (HD) protein huntingtin (HTT). Evidence has …

Cardiotoxic effects of chemotherapeutic agents with special emphasis on cisplatin

F Savio, R Cardozo, G Krygier… - … Mini Reviews (PMR), 2023 - sedici.unlp.edu.ar
Cisplatin (CPT) is a long-standing widely used chemotherapeutic alkylating agent. Its main
mechanism of action is by damaging the DNA, causing strand breaks which inhibit cell …

How Stromal Interactions Play a Role in the Quest for Human Papillomavirus Specific Cancer Therapeutics

ALA Fakunmoju - 2023 - scholarscompass.vcu.edu
High-risk human papillomaviruses (HPV), like HPV16 and HPV18, are associated with
malignant cancer growth within the oropharynx and cervix. Globally, HPV-induced cancers …

[引用][C] Meme Kanserinde Sisplatin Hücresel Yanıtının DDB2 ve DNA Polimeraz Eta Üzerinden İncelenmesi

O Aktan - 2022 - Sağlık Bilimleri Enstitüsü