[HTML][HTML] Pharmacological effects of gallic acid in health and diseases: A mechanistic review

N Kahkeshani, F Farzaei, M Fotouhi… - Iranian journal of …, 2019 - ncbi.nlm.nih.gov
Objective (s): Gallic acid is a natural phenolic compound found in several fruits and
medicinal plants. It is reported to have several health-promoting effects. This review aims to …

Mechanisms of doxorubicin-mediated reproductive toxicity–a review

UP Mohan, TP PB, STA Iqbal, S Arunachalam - Reproductive Toxicology, 2021 - Elsevier
The anticancer drug doxorubicin has been associated with several adverse side-effects
including reproductive toxicity in both genders. The current review has complied the …

[HTML][HTML] Effects of chemotherapeutic agents on male germ cells and possible ameliorating impact of antioxidants

S Ghafouri-Fard, H Shoorei, A Abak, M Seify… - Biomedicine & …, 2021 - Elsevier
Abstract Treatment of cancer in young adults is associated with several side effects,
particularly in the reproductive system. Detrimental effects of chemotherapy on the germ …

99mTc-Doxorubicin-loaded gallic acid-gold nanoparticles (99mTc-DOX-loaded GA-Au NPs) as a multifunctional theranostic agent

WI El-Ghareb, MM Swidan, IT Ibrahim… - International journal of …, 2020 - Elsevier
The development of cancer theranostic nanomedicines is recommended to concurrently
achieve and evaluate the therapeutic benefit and progress. The current work aims to …

Protective effect of gallic acid on doxorubicin-induced ovarian toxicity in mouse

RL dos Santos Silva, TLBG Lins, APO do Monte… - Reproductive …, 2023 - Elsevier
The aims of the present study were to evaluate the protective effects of gallic acid against
doxorubicin-induced ovarian toxicity in mice, and to verify the possible involvement of PI3K …

Fluvastatin attenuates doxorubicin-induced testicular toxicity in rats by reducing oxidative stress and regulating the blood–testis barrier via mTOR signaling pathway

C Gurel, GC Kuscu, A Buhur… - Human & …, 2019 - journals.sagepub.com
Doxorubicin (DOX) is an anthracycline derivative antibiotic that still frequently used in the
treatment of solid tumors and hematological malignancies. The clinical use of DOX is largely …

Naringenin palliates cisplatin and doxorubicin gonadal toxicity in male rats

AA Fouad, MMM Refaie… - … mechanisms and methods, 2019 - Taylor & Francis
Cisplatin (CP) and doxorubicin (DX) can cause testicular injury by inducing
oxidative/nitrosative stress, inflammation, and apoptosis, Naringenin (NG) has antioxidant …

Tert-butylhydroquinone attenuates doxorubicin-induced dysregulation of testicular cytoprotective and steroidogenic genes, and improves spermatogenesis in rats

GA Ujah, VU Nna, JB Suleiman, C Eleazu… - Scientific Reports, 2021 - nature.com
Doxorubicin (DOX) is a broad-spectrum chemotherapeutic drug used in the treatment of
cancers. It acts by generating reactive oxygen species in target cells. The actions are …

Cross-talk between ER stress and mitochondrial pathway mediated adriamycin-induced testicular toxicity and DA-9401 modulate adriamycin-induced apoptosis in …

KK Karna, BR Choi, JH You, YS Shin, KK Soni… - Cancer Cell …, 2019 - Springer
Background DA-9401 was prepared as a mixture of Chinese medicinal herb extracts from
roots of Morinda officinalis How (Rubiaceae), outer scales of Allium cepa L.(Liliceae) and …

Inhibitory activity of black mulberry (Morus nigra) extract against testicular, liver and kidney toxicity induced by paracetamol in mice

KA Diab, MA Fahmy, EM Hassan, ZM Hassan… - Molecular Biology …, 2020 - Springer
Black mulberry (Morus nigra) leaves is broadly used in traditional medicine worldwide.
However, there are no scientific reports regarding testicular protection, hepato-and …