[HTML][HTML] Insight into the mechanisms of action of estrogen receptor β in the breast, prostate, colon, and CNS

P Dey, RPA Barros, M Warner, A Ström… - Journal of …, 2013 - jme.bioscientifica.com
Somatostatin (SS) and urotensin II (UII) are members of two families of structurally related
neuropeptides present in all vertebrates. They exert a large array of biological activities that …

International union of basic and clinical pharmacology. XCII. Urotensin II, urotensin II–related peptide, and their receptor: From structure to function

H Vaudry, J Leprince, D Chatenet, A Fournier… - Pharmacological …, 2015 - ASPET
Urotensin II (UII) is a cyclic neuropeptide that was first isolated from the urophysis of teleost
fish on the basis of its ability to contract the hindgut. Subsequently, UII was characterized in …

[HTML][HTML] Comparative Distribution and In Vitro Activities of the Urotensin II-Related Peptides URP1 and URP2 in Zebrafish: Evidence for Their Colocalization in Spinal …

FB Quan, C Dubessy, S Galant, NB Kenigfest… - PLoS …, 2015 - journals.plos.org
Urotensin II (UII) is an evolutionarily conserved neuropeptide initially isolated from teleost
fish on the basis of its smooth muscle-contracting activity. Subsequent studies have …

Structure–activity relationships of urotensin II and URP

J Leprince, D Chatenet, C Dubessy, A Fournier… - Peptides, 2008 - Elsevier
Urotensin II (U-II) and urotensin II-related peptide (URP) are the endogenous ligands for the
orphan G-protein-coupled receptor GPR14 now renamed UT. At the periphery, U-II and/or …

Characterization of urotensin II, distribution of urotensin II, urotensin II‐related peptide and UT receptor mRNAs in mouse: evidence of urotensin II at the …

C Dubessy, D Cartier, B Lectez… - Journal of …, 2008 - Wiley Online Library
Abstract Urotensin II (UII) and UII‐related peptide (URP) are paralog neuropeptides whose
existence and distribution in mouse have not yet been investigated. In this study, we showed …

Cardiorenovascular effects of urotensin II and the relevance of the UT receptor

M Tölle, M van der Giet - Peptides, 2008 - Elsevier
Urotensin II (U-II) is a vasoactive peptide with many potent effects in the cardiorenovascular
system. U-II activates a G-protein-coupled receptor termed UT. UT and U-II are highly …

Biochemical and functional characterization of high‐affinity urotensin II receptors in rat cortical astrocytes

H Castel, M Diallo, D Chatenet… - Journal of …, 2006 - Wiley Online Library
The urotensin II (UII) gene is primarily expressed in the central nervous system, but the
functions of UII in the brain remain elusive. Here, we show that cultured rat astrocytes …

Occurrence of two distinct urotensin II-related peptides in zebrafish provides new insight into the evolutionary history of the urotensin II gene family

C Parmentier, E Hameury, C Dubessy, FB Quan… - …, 2011 - academic.oup.com
The urotensin II (UII) family is currently known to consist of two paralogous peptides, namely
UII and UII-related peptide (URP). In contrast to UII, which has been identified in all …

Biological properties and functional determinants of the urotensin II receptor

CD Proulx, BJ Holleran, P Lavigne, E Escher… - Peptides, 2008 - Elsevier
The urotensin II receptor (UT) is a member of the G protein-coupled receptor (GPCR) family
and binds the cyclic undecapeptide urotensin II (U-II) as well as the octapeptide urotensin II …

Structure− Activity Relationships of a Novel Series of Urotensin II Analogues: Identification of a Urotensin II Antagonist

D Chatenet, C Dubessy, C Boularan… - Journal of medicinal …, 2006 - ACS Publications
Urotensin II (U-II) is a potent vasoconstrictor peptide which has been identified as the
endogenous ligand for the orphan G protein-coupled receptor GPR14 now renamed UT …