We describe the collection of cohorts together with the analysis plan for an update of the
fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource …

Sleep apnea is a sleep related disorder that significantly affects the population.
Polysomnography, the gold standard, is expensive, inaccessible, uncomfortable and an …

Aims Apnoea–hypopnoea index (AHI), the universal clinical metric of sleep apnoea severity,
poorly predicts the adverse outcomes of sleep apnoea, potentially because the AHI, a …

OBJECTIVES To develop an evidence‐based definition of sarcopenia that can facilitate
identification of older adults at risk for clinically relevant outcomes (eg, self‐reported mobility …

Objective The gold standard for diagnosing sleep disorders is polysomnography, which
generates extensive data about biophysical changes occurring during sleep. We developed …

Background. Low muscle mass and weakness are common and potentially disabling in
older adults, but in order to become recognized as a clinical condition, criteria for diagnosis …

Bone mineral density (BMD) assessed by DXA is used to evaluate bone health. In children,
total body (TB) measurements are commonly used; in older individuals, BMD at the lumbar …

Context Survival estimates help individualize goals of care for geriatric patients, but life
tables fail to account for the great variability in survival. Physical performance measures …

Background. Weakness is common and contributes to disability, but no consensus exists
regarding a strength cutpoint to identify persons at high risk. This analysis, conducted as part …

Background. Functional independence with aging is an important goal for individuals and
society. Simple prognostic indicators can inform health promotion and care planning, but …