Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

Although immunotherapy research to date has focused largely on T cells, there is mounting
evidence that tumour-infiltrating B cells and plasma cells (collectively referred to as tumour …

The germinal centre (GC) response is critical for the generation of affinity-matured plasma
cells and memory B cells capable of mediating long-term protective immunity …

Adaptive immune responses to SARS-CoV-2 infection have been extensively characterized
in blood; however, most functions of protective immunity must be accomplished in tissues …

Among human leukocyte antigen (HLA)-associated disorders, celiac disease has an
immunopathogenesis that is particularly well understood. The condition is characterized by …

Tissue-resident immune cells span both myeloid and lymphoid cell lineages, have been
found in multiple human tissues, and play integral roles at all stages of the immune …

Infants and young children are more susceptible to common respiratory pathogens than
adults but can fare better against novel pathogens like severe acute respiratory syndrome …

Immunological memory is a composite of lasting antibody titers maintained by plasma cells
in conjunction with memory T and B cells. Memory B cells are a critical reservoir for plasma …

The upper airway is an important site of infection, but immune memory in the human upper
airway is poorly understood, with implications for COVID-19 and many other human …

While blood antibodies mediate protective immunity in most organs, whether they protect
nasal surfaces in the upper airway is unclear. Using multiple viral infection models in mice …